Paroxetine: population pharmacokinetic analysis in late-life depression using sparse concentration sampling

AIM: To develop a population pharmacokinetic (PK) model using sparse sampling of long-term treatment with paroxetine in elderly depressed subjects, incorporating CYP2D6 genotype as well as other covariates. METHODS: Elderly subjects (age ≥70 years) with nonpsychotic, nonbipolar major depressive diso...

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Main Authors: Feng, Yan, Pollock, Bruce G, Ferrell, Robert E, Kimak, Mark A, Reynolds, Charles F, Bies, Robert R
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2006
Teme:
Pharmacokinetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885048/
https://ncbi.nlm.nih.gov/pubmed/16669849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2006.02629.x
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