The Moonwalker Mouse: New Insights into TRPC3 Function, Cerebellar Development, and Ataxia

Por Becker, Esther B. E.
Publicado em 2014

From mice to men: TRPC3 in cerebellar ataxia

Por Becker, Esther B. E.
Publicado no Cerebellum (2017)

Pin1 in Neuronal Apoptosis

Por Becker, Esther B.E., Bonni, Azad
Publicado em 2007

Do Mutations in the Murine Ataxia Gene TRPC3 Cause Cerebellar Ataxia in Humans?

Por Fogel, Brent L., Hanson, Sonya M., Becker, Esther B. E.
Publicado no Mov Disord (2014)

Modeling Suggests TRPC3 Hydrogen Bonding and Not Phosphorylation Contributes to the Ataxia Phenotype of the Moonwalker Mouse

Por Hanson, Sonya M., Sansom, Mark S. P., Becker, Esther B. E.
Publicado no Biochemistry (2015)

Induced pluripotent stem cell technology for modelling and therapy of cerebellar ataxia

Por Watson, Lauren M., Wong, Maggie M. K., Becker, Esther B. E.
Publicado no Open Biol (2015)

Recent advances in modelling of cerebellar ataxia using induced pluripotent stem cells

Por Wong, Maggie M. K., Watson, Lauren M., Becker, Esther B. E.
Publicado no J Neurol Neuromedicine (2017)

Reciprocal regulation of two G protein-coupled receptors sensing extracellular concentrations of Ca(2+) and H(+)

Por Wei, Wei-Chun, Jacobs, Benjamin, Becker, Esther B. E., Glitsch, Maike D.
Publicado no Proc Natl Acad Sci U S A (2015)

A Simplified Method for Generating Purkinje Cells from Human-Induced Pluripotent Stem Cells

Por Watson, Lauren M., Wong, Maggie M. K., Vowles, Jane, Cowley, Sally A., Becker, Esther B. E.
Publicado no Cerebellum (2018)

A JIP3-Regulated GSK3β/DCX Signaling Pathway Restricts Axon Branching

Por Bilimoria, Parizad M., de la Torre-Ubieta, Luis, Ikeuchi, Yoshiho, Becker, Esther B. E., Reiner, Orly, Bonni, Azad
Publicado em 2010

Bim Regulation of Lumen Formation in Cultured Mammary Epithelial Acini Is Targeted by Oncogenes

Por Reginato, Mauricio J., Mills, Kenna R., Becker, Esther B. E., Lynch, Danielle K., Bonni, Azad, Muthuswamy, Senthil K., Brugge, Joan S.
Publicado em 2005

Early Onset of Ataxia in Moonwalker Mice Is Accompanied by Complete Ablation of Type II Unipolar Brush Cells and Purkinje Cell Dysfunction

Por Sekerková, Gabriella, Kim, Jin-Ah, Nigro, Maximiliano J., Becker, Esther B. E., Hartmann, Jana, Birnbaumer, Lutz, Mugnaini, Enrico, Martina, Marco
Publicado em 2013

The mutant Moonwalker TRPC3 channel links calcium signaling to lipid metabolism in the developing cerebellum

Por Dulneva, Anna, Lee, Sheena, Oliver, Peter L., Di Gleria, Katalin, Kessler, Benedikt M., Davies, Kay E., Becker, Esther B. E.
Publicado no Hum Mol Genet (2015)

Candidate Screening of the TRPC3 Gene in Cerebellar Ataxia

Por Becker, Esther B. E., Fogel, Brent L., Rajakulendran, Sanjeev, Dulneva, Anna, Hanna, Michael G., Perlman, Susan L., Geschwind, Daniel H., Davies, Kay E.
Publicado em 2011

Oxr1 Is Essential for Protection against Oxidative Stress-Induced Neurodegeneration

Por Oliver, Peter L., Finelli, Mattéa J., Edwards, Benjamin, Bitoun, Emmanuelle, Butts, Darcy L., Becker, Esther B. E., Cheeseman, Michael T., Davies, Ben, Davies, Kay E.
Publicado em 2011

Functional expression of calcium‐permeable canonical transient receptor potential 4‐containing channels promotes migration of medulloblastoma cells

Por Wei, Wei‐Chun, Huang, Wan‐Chen, Lin, Yu‐Ping, Becker, Esther B. E., Ansorge, Olaf, Flockerzi, Veit, Conti, Daniele, Cenacchi, Giovanna, Glitsch, Maike D.
Publicado no J Physiol (2017)

A point mutation in TRPC3 causes abnormal Purkinje cell development and cerebellar ataxia in moonwalker mice

Por Becker, Esther B. E., Oliver, Peter L., Glitsch, Maike D., Banks, Gareth T., Achilli, Francesca, Hardy, Andrea, Nolan, Patrick M., Fisher, Elizabeth M. C., Davies, Kay E.
Publicado em 2009

Contactin-associated protein-2 antibodies in non-paraneoplastic cerebellar ataxia

Por Becker, Esther B E, Zuliani, Luigi, Pettingill, Rosemary, Lang, Bethan, Waters, Patrick, Dulneva, Anna, Sobott, Frank, Wardle, Mark, Graus, Francesc, Bataller, Luis, Robertson, Neil P, Vincent, Angela
Publicado em 2012

A Transient Translaminar GABAergic Interneuron Circuit Connects Thalamocortical Recipient Layers in Neonatal Somatosensory Cortex

Por Marques-Smith, Andre, Lyngholm, Daniel, Kaufmann, Anna-Kristin, Stacey, Jacqueline A., Hoerder-Suabedissen, Anna, Becker, Esther B.E., Wilson, Michael C., Molnár, Zoltán, Butt, Simon J.B.
Publicado no Neuron (2016)

Dominant Mutations in GRM1 Cause Spinocerebellar Ataxia Type 44

Por Watson, Lauren M., Bamber, Elizabeth, Schnekenberg, Ricardo Parolin, Williams, Jonathan, Bettencourt, Conceição, Lickiss, Jennifer, Fawcett, Katherine, Clokie, Samuel, Wallis, Yvonne, Clouston, Penny, Sims, David, Houlden, Henry, Becker, Esther B.E., Németh, Andrea H.
Publicado no Am J Hum Genet (2017)