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Pin1 in Neuronal Apoptosis

While the role of the prolyl isomerase Pin1 in dividing cells has long been recognized, Pin1’s function in postmitotic neurons is poorly understood. We have identified a novel mechanism by which Pin1 mediates activation of the mitochondrial cell death machinery specifically in neurons. This perspect...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Becker, Esther B.E., Bonni, Azad
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743181/
https://ncbi.nlm.nih.gov/pubmed/17568190
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