Reversing Platinum Resistance in High-Grade Serous Ovarian Carcinoma: Targeting BRCA and the Homologous Recombination System

door Wiedemeyer, W. Ruprecht, Beach, Jessica A., Karlan, Beth Y.
Gepubliceerd in 2014

Correlation of Glucocorticoid-mediated E4BP4 upregulation with altered expression of pro- and anti-apoptotic genes in CEM human lymphoblastic leukemia cells

door Beach, Jessica A., Nary, Laura J., Hovanessian, Rebeka, Medh, Rheem D.
Gepubliceerd in 2014

E4BP4 facilitates glucocorticoid-evoked apoptosis of human leukemic CEM cells via upregulation of Bim

door Beach, Jessica A, Nary, Laura J, Hirakawa, Yasuko, Holland, Eli, Hovanessian, Rebeka, Medh, Rheem D
Gepubliceerd in 2011

Suboptimal cytoreduction in ovarian carcinoma is associated with molecular pathways characteristic of increased stromal activation

door Liu, Zhenqiu, Beach, Jessica A., Agadjanian, Hasmik, Jia, Dongyu, Aspuria, Paul-Joseph, Karlan, Beth Y., Orsulic, Sandra
Gepubliceerd in Gynecol Oncol (2015)

Sphingosine kinase 1 is required for TGF-β mediated fibroblast-to-myofibroblast differentiation in ovarian cancer

door Beach, Jessica A., Aspuria, Paul-Joseph P., Cheon, Dong-Joo, Lawrenson, Kate, Agadjanian, Hasmik, Walsh, Christine S., Karlan, Beth Y., Orsulic, Sandra
Gepubliceerd in Oncotarget (2015)

ADAM12 is a prognostic factor associated with an aggressive molecular subtype of high-grade serous ovarian carcinoma

door Cheon, Dong-Joo, Li, Andrew J., Beach, Jessica A., Walts, Ann E., Tran, Hang, Lester, Jenny, Karlan, Beth Y., Orsulic, Sandra
Gepubliceerd in Carcinogenesis (2015)

Differential expression of argininosuccinate synthetase in serous and non‐serous ovarian carcinomas

door Cheon, Dong‐Joo, Walts, Ann E, Beach, Jessica A, Lester, Jenny, Bomalaski, John S, Walsh, Christine S, Ruprecht Wiedemeyer, W, Karlan, Beth Y, Orsulic, Sandra
Gepubliceerd in J Pathol Clin Res (2014)

A collagen-remodeling gene signature regulated by TGFβ signaling is associated with metastasis and poor survival in serous ovarian cancer

door Cheon, Dong-Joo, Tong, Yunguang, Sim, Myung-Shin, Dering, Judy, Berel, Dror, Cui, Xiaojiang, Lester, Jenny, Beach, Jessica A., Tighiouart, Mourad, Walts, Ann E., Karlan, Beth Y., Orsulic, Sandra
Gepubliceerd in 2013

Succinate dehydrogenase inhibition leads to epithelial-mesenchymal transition and reprogrammed carbon metabolism

door Aspuria, Paul-Joseph P, Lunt, Sophia Y, Väremo, Leif, Vergnes, Laurent, Gozo, Maricel, Beach, Jessica A, Salumbides, Brenda, Reue, Karen, Wiedemeyer, W Ruprecht, Nielsen, Jens, Karlan, Beth Y, Orsulic, Sandra
Gepubliceerd in Cancer Metab (2014)

Going to extremes: determinants of extraordinary response and survival in patients with cancer

door Saner, Flurina A. M., Herschtal, Alan, Nelson, Brad H., deFazio, Anna, Goode, Ellen L., Ramus, Susan J., Pandey, Ahwan, Beach, Jessica A., Fereday, Sian, Berchuck, Andrew, Lheureux, Stephanie, Pearce, Celeste Leigh, Pharoah, Paul D., Pike, Malcolm C., Garsed, Dale W., Bowtell, David D. L.
Gepubliceerd in Nat Rev Cancer (2019)

Clinical MDR1 inhibitors enhance Smac-mimetic bioavailability to kill murine LSCs and improve survival in AML models

door Morrish, Emma, Copeland, Anthony, Moujalled, Donia M., Powell, Jason A., Silke, Natasha, Lin, Ann, Jarman, Kate E., Sandow, Jarrod J., Ebert, Gregor, Mackiewicz, Liana, Beach, Jessica A., Christie, Elizabeth L., Lewis, Alexander C., Pomilio, Giovanna, Fischer, Karla C., MacPherson, Laura, Bowtell, David D. L., Webb, Andrew I., Pellegrini, Marc, Dawson, Mark A., Pitson, Stuart M., Wei, Andrew H., Silke, John, Brumatti, Gabriela
Gepubliceerd in Blood Adv (2020)