Reversing Platinum Resistance in High-Grade Serous Ovarian Carcinoma: Targeting BRCA and the Homologous Recombination System

Por Wiedemeyer, W. Ruprecht, Beach, Jessica A., Karlan, Beth Y.
Publicado em 2014

Correlation of Glucocorticoid-mediated E4BP4 upregulation with altered expression of pro- and anti-apoptotic genes in CEM human lymphoblastic leukemia cells

Por Beach, Jessica A., Nary, Laura J., Hovanessian, Rebeka, Medh, Rheem D.
Publicado em 2014

E4BP4 facilitates glucocorticoid-evoked apoptosis of human leukemic CEM cells via upregulation of Bim

Por Beach, Jessica A, Nary, Laura J, Hirakawa, Yasuko, Holland, Eli, Hovanessian, Rebeka, Medh, Rheem D
Publicado em 2011

Suboptimal cytoreduction in ovarian carcinoma is associated with molecular pathways characteristic of increased stromal activation

Por Liu, Zhenqiu, Beach, Jessica A., Agadjanian, Hasmik, Jia, Dongyu, Aspuria, Paul-Joseph, Karlan, Beth Y., Orsulic, Sandra
Publicado no Gynecol Oncol (2015)

Sphingosine kinase 1 is required for TGF-β mediated fibroblast-to-myofibroblast differentiation in ovarian cancer

Por Beach, Jessica A., Aspuria, Paul-Joseph P., Cheon, Dong-Joo, Lawrenson, Kate, Agadjanian, Hasmik, Walsh, Christine S., Karlan, Beth Y., Orsulic, Sandra
Publicado no Oncotarget (2015)

ADAM12 is a prognostic factor associated with an aggressive molecular subtype of high-grade serous ovarian carcinoma

Por Cheon, Dong-Joo, Li, Andrew J., Beach, Jessica A., Walts, Ann E., Tran, Hang, Lester, Jenny, Karlan, Beth Y., Orsulic, Sandra
Publicado no Carcinogenesis (2015)

Differential expression of argininosuccinate synthetase in serous and non‐serous ovarian carcinomas

Por Cheon, Dong‐Joo, Walts, Ann E, Beach, Jessica A, Lester, Jenny, Bomalaski, John S, Walsh, Christine S, Ruprecht Wiedemeyer, W, Karlan, Beth Y, Orsulic, Sandra
Publicado no J Pathol Clin Res (2014)

A collagen-remodeling gene signature regulated by TGFβ signaling is associated with metastasis and poor survival in serous ovarian cancer

Por Cheon, Dong-Joo, Tong, Yunguang, Sim, Myung-Shin, Dering, Judy, Berel, Dror, Cui, Xiaojiang, Lester, Jenny, Beach, Jessica A., Tighiouart, Mourad, Walts, Ann E., Karlan, Beth Y., Orsulic, Sandra
Publicado em 2013

Succinate dehydrogenase inhibition leads to epithelial-mesenchymal transition and reprogrammed carbon metabolism

Por Aspuria, Paul-Joseph P, Lunt, Sophia Y, Väremo, Leif, Vergnes, Laurent, Gozo, Maricel, Beach, Jessica A, Salumbides, Brenda, Reue, Karen, Wiedemeyer, W Ruprecht, Nielsen, Jens, Karlan, Beth Y, Orsulic, Sandra
Publicado no Cancer Metab (2014)

Going to extremes: determinants of extraordinary response and survival in patients with cancer

Por Saner, Flurina A. M., Herschtal, Alan, Nelson, Brad H., deFazio, Anna, Goode, Ellen L., Ramus, Susan J., Pandey, Ahwan, Beach, Jessica A., Fereday, Sian, Berchuck, Andrew, Lheureux, Stephanie, Pearce, Celeste Leigh, Pharoah, Paul D., Pike, Malcolm C., Garsed, Dale W., Bowtell, David D. L.
Publicado no Nat Rev Cancer (2019)

Clinical MDR1 inhibitors enhance Smac-mimetic bioavailability to kill murine LSCs and improve survival in AML models

Por Morrish, Emma, Copeland, Anthony, Moujalled, Donia M., Powell, Jason A., Silke, Natasha, Lin, Ann, Jarman, Kate E., Sandow, Jarrod J., Ebert, Gregor, Mackiewicz, Liana, Beach, Jessica A., Christie, Elizabeth L., Lewis, Alexander C., Pomilio, Giovanna, Fischer, Karla C., MacPherson, Laura, Bowtell, David D. L., Webb, Andrew I., Pellegrini, Marc, Dawson, Mark A., Pitson, Stuart M., Wei, Andrew H., Silke, John, Brumatti, Gabriela
Publicado no Blood Adv (2020)