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Correlation of Glucocorticoid-mediated E4BP4 upregulation with altered expression of pro- and anti-apoptotic genes in CEM human lymphoblastic leukemia cells
In C.elegans, motoneuron apoptosis is regulated via a ces-2 – ces-1 – egl-1 pathway. We tested whether human CEM lymphoblastic leukemia cells undergo apoptosis via an analogous pathway. We have previously shown that E4BP4, a ces-2 ortholog, mediates glucocorticoid (GC)-dependent upregulation of BIM,...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4150740/ https://ncbi.nlm.nih.gov/pubmed/25101525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2014.07.103 |
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