Calcium-dependent upregulation of E4BP4 expression correlates with glucocorticoid-evoked apoptosis of human leukemic CEM cells

Glucocorticoid (GC)-evoked apoptosis of T-lymphoid cells is preceded by increases in the intracellular Ca(2+) concentration ([Ca(2+)](i)), which may contribute to apoptosis. This report demonstrates that GC-mediated upregulation of the bZIP transcriptional repressor gene, E4BP4, is dependent on [Ca(...

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Detalhes bibliográficos
Main Authors: Priceman, Saul J., Kirzner, Jonathan D., Nary, Laura J., Morris, Devin, Shankar, Deepa B., Sakamoto, Kathleen M., Medh, Rheem D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763529/
https://ncbi.nlm.nih.gov/pubmed/16630563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.03.169
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