The structure of apo protein-tyrosine phosphatase 1B C215S mutant: More than just an S → O change

by Scapin, Giovanna, Patel, Sangita, Patel, Vira, Kennedy, Brian, Asante-Appiah, Ernest
Published 2001

Unraveling the structural basis of grazoprevir potency against clinically relevant substitutions in hepatitis C virus NS3/4A protease from genotype 1a

by Guo, Zhuyan, Black, Stuart, Hu, Yuan, McMonagle, Patricia, Ingravallo, Paul, Chase, Robert, Curry, Stephanie, Asante-Appiah, Ernest
Published in J Biol Chem (2017)

Antiviral Activity and Resistance Analysis of NS3/4A Protease Inhibitor Grazoprevir and NS5A Inhibitor Elbasvir in Hepatitis C Virus GT4 Replicons

by Asante-Appiah, Ernest, Curry, Stephanie, McMonagle, Patricia, Ingravallo, Paul, Chase, Robert, Nickle, David, Qiu, Ping, Howe, Anita, Lahser, Frederick C.
Published in Antimicrob Agents Chemother (2017)

Interplay of Amino Acid Residues at Positions 28 and 31 in NS5A Defines Resistance Pathways in Hepatitis C Virus Genotype 2

by Asante-Appiah, Ernest, Ingravallo, Paul, McMonagle, Patricia, Bystol, Karin, Xia, Ellen, Curry, Stephanie, Qiu, Ping, Black, Stuart, Chase, Robert, Liu, Rong, Lahser, Fred
Published in Antimicrob Agents Chemother (2019)

Review of Doravirine Resistance Patterns Identified in Participants During Clinical Development

by Martin, Elizabeth Anne, Lai, Ming-Tain, Ngo, Winnie, Feng, Meizhen, Graham, Donald, Hazuda, Daria J., Kumar, Sushma, Hwang, Carey, Sklar, Peter, Asante-Appiah, Ernest
Published in J Acquir Immune Defic Syndr (2020)

Kinetic Analyses Reveal Potent and Early Blockade of Hepatitis C Virus Assembly by NS5A Inhibitors

by McGivern, David R., Masaki, Takahiro, Williford, Sara, Ingravallo, Paul, Feng, Zongdi, Lahser, Frederick, Asante-Appiah, Ernest, Neddermann, Petra, Francesco, Raffaele De, Howe, Anita Y., Lemon, Stanley M.
Published 2014

The Combination of Grazoprevir, a Hepatitis C Virus (HCV) NS3/4A Protease Inhibitor, and Elbasvir, an HCV NS5A Inhibitor, Demonstrates a High Genetic Barrier to Resistance in HCV G...

by Lahser, Frederick C., Bystol, Karin, Curry, Stephanie, McMonagle, Patricia, Xia, Ellen, Ingravallo, Paul, Chase, Robert, Liu, Rong, Black, Todd, Hazuda, Daria, Howe, Anita Y. M., Asante-Appiah, Ernest
Published in Antimicrob Agents Chemother (2016)

Evolutionary pathways to NS5A inhibitor resistance in genotype 1 hepatitis C virus

by Zhou, Shuntai, Williford, Sara E., McGivern, David R., Burch, Christina L., Hu, Fengyu, Benzine, Tiffany, Ingravallo, Paul, Asante-Appiah, Ernest, Howe, Anita Y.M., Swanstrom, Ronald, Lemon, Stanley M.
Published in Antiviral Res (2018)

In Vitro Antiviral Profile of Ruzasvir, a Potent and Pangenotype Inhibitor of Hepatitis C Virus NS5A

by Asante-Appiah, Ernest, Liu, Rong, Curry, Stephanie, McMonagle, Patricia, Agrawal, Sony, Carr, Donna, Rokosz, Laura, Lahser, Frederick, Bystol, Karin, Chase, Robert, Black, Stuart, Ferrari, Eric, Ingravallo, Paul, Tong, Ling, Yu, Wensheng, Kozlowski, Joseph
Published in Antimicrob Agents Chemother (2018)

In Vitro Characterization of MK-1439, a Novel HIV-1 Nonnucleoside Reverse Transcriptase Inhibitor

by Lai, Ming-Tain, Feng, Meizhen, Falgueyret, Jean-Pierre, Tawa, Paul, Witmer, Marc, DiStefano, Daniel, Li, Yuan, Burch, Jason, Sachs, Nancy, Lu, Meiqing, Cauchon, Elizabeth, Campeau, Louis-Charles, Grobler, Jay, Yan, Youwei, Ducharme, Yves, Côté, Bernard, Asante-Appiah, Ernest, Hazuda, Daria J., Miller, Michael D.
Published 2014

Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers

by Wang, I-Ming, Zhang, Bin, Yang, Xia, Zhu, Jun, Stepaniants, Serguei, Zhang, Chunsheng, Meng, Qingying, Peters, Mette, He, Yudong, Ni, Chester, Slipetz, Deborah, Crackower, Michael A, Houshyar, Hani, Tan, Christopher M, Asante-Appiah, Ernest, O'Neill, Gary, Jane Luo, Mingjuan, Thieringer, Rolf, Yuan, Jeffrey, Chiu, Chi-Sung, Yee Lum, Pek, Lamb, John, Boie, Yves, Wilkinson, Hilary A, Schadt, Eric E, Dai, Hongyue, Roberts, Christopher
Published 2012

Efficacy and safety of elbasvir/grazoprevir in treatment‐naive Chinese adults with hepatitis C virus infection: A randomized trial

by Wei, Lai, Jia, Ji Dong, Duan, Zhong Ping, Wang, Fu Sheng, Niu, Jun Qi, Xie, Wen, Huang, Wen Xiang, Zhang, Ming Xiang, Huang, Yan, Wang, Mao Rong, Wu, Shan Ming, Zhao, Ying Ren, Jia, Zhan Sheng, Zhao, Xu Min, Mu, Sheng Mei, Liang, Li Wen, Wang, Zaiqi, Puenpatom, Amy, Hwang, Peggy, Robertson, Michael N., Ingravallo, Paul, Asante‐Appiah, Ernest, Wei, Bo, Evans, Barbara, Hanna, George J., Talwani, Rohit
Published in JGH Open (2020)