The structure of apo protein-tyrosine phosphatase 1B C215S mutant: More than just an S → O change

gan Scapin, Giovanna, Patel, Sangita, Patel, Vira, Kennedy, Brian, Asante-Appiah, Ernest
Cyhoeddwyd 2001

Unraveling the structural basis of grazoprevir potency against clinically relevant substitutions in hepatitis C virus NS3/4A protease from genotype 1a

gan Guo, Zhuyan, Black, Stuart, Hu, Yuan, McMonagle, Patricia, Ingravallo, Paul, Chase, Robert, Curry, Stephanie, Asante-Appiah, Ernest
Cyhoeddwyd yn J Biol Chem (2017)

Antiviral Activity and Resistance Analysis of NS3/4A Protease Inhibitor Grazoprevir and NS5A Inhibitor Elbasvir in Hepatitis C Virus GT4 Replicons

gan Asante-Appiah, Ernest, Curry, Stephanie, McMonagle, Patricia, Ingravallo, Paul, Chase, Robert, Nickle, David, Qiu, Ping, Howe, Anita, Lahser, Frederick C.
Cyhoeddwyd yn Antimicrob Agents Chemother (2017)

Interplay of Amino Acid Residues at Positions 28 and 31 in NS5A Defines Resistance Pathways in Hepatitis C Virus Genotype 2

gan Asante-Appiah, Ernest, Ingravallo, Paul, McMonagle, Patricia, Bystol, Karin, Xia, Ellen, Curry, Stephanie, Qiu, Ping, Black, Stuart, Chase, Robert, Liu, Rong, Lahser, Fred
Cyhoeddwyd yn Antimicrob Agents Chemother (2019)

Review of Doravirine Resistance Patterns Identified in Participants During Clinical Development

gan Martin, Elizabeth Anne, Lai, Ming-Tain, Ngo, Winnie, Feng, Meizhen, Graham, Donald, Hazuda, Daria J., Kumar, Sushma, Hwang, Carey, Sklar, Peter, Asante-Appiah, Ernest
Cyhoeddwyd yn J Acquir Immune Defic Syndr (2020)

Kinetic Analyses Reveal Potent and Early Blockade of Hepatitis C Virus Assembly by NS5A Inhibitors

gan McGivern, David R., Masaki, Takahiro, Williford, Sara, Ingravallo, Paul, Feng, Zongdi, Lahser, Frederick, Asante-Appiah, Ernest, Neddermann, Petra, Francesco, Raffaele De, Howe, Anita Y., Lemon, Stanley M.
Cyhoeddwyd 2014

The Combination of Grazoprevir, a Hepatitis C Virus (HCV) NS3/4A Protease Inhibitor, and Elbasvir, an HCV NS5A Inhibitor, Demonstrates a High Genetic Barrier to Resistance in HCV G...

gan Lahser, Frederick C., Bystol, Karin, Curry, Stephanie, McMonagle, Patricia, Xia, Ellen, Ingravallo, Paul, Chase, Robert, Liu, Rong, Black, Todd, Hazuda, Daria, Howe, Anita Y. M., Asante-Appiah, Ernest
Cyhoeddwyd yn Antimicrob Agents Chemother (2016)

Evolutionary pathways to NS5A inhibitor resistance in genotype 1 hepatitis C virus

gan Zhou, Shuntai, Williford, Sara E., McGivern, David R., Burch, Christina L., Hu, Fengyu, Benzine, Tiffany, Ingravallo, Paul, Asante-Appiah, Ernest, Howe, Anita Y.M., Swanstrom, Ronald, Lemon, Stanley M.
Cyhoeddwyd yn Antiviral Res (2018)

In Vitro Antiviral Profile of Ruzasvir, a Potent and Pangenotype Inhibitor of Hepatitis C Virus NS5A

gan Asante-Appiah, Ernest, Liu, Rong, Curry, Stephanie, McMonagle, Patricia, Agrawal, Sony, Carr, Donna, Rokosz, Laura, Lahser, Frederick, Bystol, Karin, Chase, Robert, Black, Stuart, Ferrari, Eric, Ingravallo, Paul, Tong, Ling, Yu, Wensheng, Kozlowski, Joseph
Cyhoeddwyd yn Antimicrob Agents Chemother (2018)

In Vitro Characterization of MK-1439, a Novel HIV-1 Nonnucleoside Reverse Transcriptase Inhibitor

gan Lai, Ming-Tain, Feng, Meizhen, Falgueyret, Jean-Pierre, Tawa, Paul, Witmer, Marc, DiStefano, Daniel, Li, Yuan, Burch, Jason, Sachs, Nancy, Lu, Meiqing, Cauchon, Elizabeth, Campeau, Louis-Charles, Grobler, Jay, Yan, Youwei, Ducharme, Yves, Côté, Bernard, Asante-Appiah, Ernest, Hazuda, Daria J., Miller, Michael D.
Cyhoeddwyd 2014

Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers

gan Wang, I-Ming, Zhang, Bin, Yang, Xia, Zhu, Jun, Stepaniants, Serguei, Zhang, Chunsheng, Meng, Qingying, Peters, Mette, He, Yudong, Ni, Chester, Slipetz, Deborah, Crackower, Michael A, Houshyar, Hani, Tan, Christopher M, Asante-Appiah, Ernest, O'Neill, Gary, Jane Luo, Mingjuan, Thieringer, Rolf, Yuan, Jeffrey, Chiu, Chi-Sung, Yee Lum, Pek, Lamb, John, Boie, Yves, Wilkinson, Hilary A, Schadt, Eric E, Dai, Hongyue, Roberts, Christopher
Cyhoeddwyd 2012

Efficacy and safety of elbasvir/grazoprevir in treatment‐naive Chinese adults with hepatitis C virus infection: A randomized trial

gan Wei, Lai, Jia, Ji Dong, Duan, Zhong Ping, Wang, Fu Sheng, Niu, Jun Qi, Xie, Wen, Huang, Wen Xiang, Zhang, Ming Xiang, Huang, Yan, Wang, Mao Rong, Wu, Shan Ming, Zhao, Ying Ren, Jia, Zhan Sheng, Zhao, Xu Min, Mu, Sheng Mei, Liang, Li Wen, Wang, Zaiqi, Puenpatom, Amy, Hwang, Peggy, Robertson, Michael N., Ingravallo, Paul, Asante‐Appiah, Ernest, Wei, Bo, Evans, Barbara, Hanna, George J., Talwani, Rohit
Cyhoeddwyd yn JGH Open (2020)