IκBβ is an essential co-activator for LPS-induced IL-1β transcription in vivo

по Scheibel, Melanie, Klein, Bettina, Merkle, Heidrun, Schulz, Manon, Fritsch, Ralph, Greten, Florian R., Arkan, Melek C., Schneider, Günter, Schmid, Roland M.
Опубликовано 2010

Opposing functions of IKKβ during acute and chronic intestinal inflammation

по Eckmann, Lars, Nebelsiek, Tim, Fingerle, Alexander A., Dann, Sara M., Mages, Jörg, Lang, Roland, Robine, Sylvie, Kagnoff, Martin F., Schmid, Roland M., Karin, Michael, Arkan, Melek C., Greten, Florian R.
Опубликовано 2008

NF-κB is a negative regulator of IL-1β secretion as revealed by genetic and pharmacological inhibition of IKKβ

по Greten, Florian R., Arkan, Melek C., Bollrath, Julia, Hsu, Li-Chung, Goode, Jason, Miething, Cornelius, Göktuna, Serkan I., Neuenhahn, Michael, Fierer, Joshua, Paxian, Stephan, Van Rooijen, Nico, Xu, Yajun, Cain, Timothy O’, Jaffee, Bruce B., Busch, Dirk H., Duyster, Justus, Schmid, Roland M., Eckmann, Lars, Karin, Michael
Опубликовано 2007

Colon tumor cell death causes mTOR dependence by paracrine P2X(4) stimulation

по Schmitt, Mark, Ceteci, Fatih, Gupta, Jalaj, Pesic, Marina, Böttger, Tim W., Nicolas, Adele M., Kennel, Kilian B., Engel, Esther, Schewe, Matthias, Kirisozu, Asude, Petrocelli, Valentina, Dabiri, Yasamin, Varga, Julia, Ramakrishnan, Mallika, Karimova, Madina, Ablasser, Andrea, Sato, Toshiro, Arkan, Melek C., de Sauvage, Frederic J., Greten, Florian R.
Опубликовано в: Nature (2022)

IKKα Promotes Intestinal Tumorigenesis by Limiting Recruitment of M1-like Polarized Myeloid Cells

по Göktuna, Serkan I., Canli, Ozge, Bollrath, Julia, Fingerle, Alexander A., Horst, David, Diamanti, Michaela A., Pallangyo, Charles, Bennecke, Moritz, Nebelsiek, Tim, Mankan, Arun K., Lang, Roland, Artis, David, Hu, Yinling, Patzelt, Thomas, Ruland, Jürgen, Kirchner, Thomas, Taketo, M. Mark, Chariot, Alain, Arkan, Melek C., Greten, Florian R.
Опубликовано в: Cell Rep (2014)

High-fat diet-mediated dysbiosis promotes intestinal carcinogenesis independent of obesity

по Schulz, Manon D., Atay, Çigdem, Heringer, Jessica, Romrig, Franziska K., Schwitalla, Sarah, Aydin, Begüm, Ziegler, Paul K., Varga, Julia, Reindl, Wolfgang, Pommerenke, Claudia, Salinas-Riester, Gabriela, Böck, Andreas, Alpert, Carl, Blaut, Michael, Polson, Sara C., Brandl, Lydia, Kirchner, Thomas, Greten, Florian R., Polson, Shawn W., Arkan, Melek C.
Опубликовано в: Nature (2014)

Loss of acinar cell IKKα triggers spontaneous pancreatitis in mice

по Li, Ning, Wu, Xuefeng, Holzer, Ryan G., Lee, Jun-Hee, Todoric, Jelena, Park, Eek-Joong, Ogata, Hisanobu, Gukovskaya, Anna S., Gukovsky, Ilya, Pizzo, Donald P., VandenBerg, Scott, Tarin, David, Atay, Çiǧdem, Arkan, Melek C., Deerinck, Thomas J., Moscat, Jorge, Diaz-Meco, Maria, Dawson, David, Erkan, Mert, Kleeff, Jörg, Karin, Michael
Опубликовано 2013

Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis

по Ziegler, Paul K., Bollrath, Julia, Pallangyo, Charles K., Matsutani, Takaji, Canli, Özge, De Oliveira, Tiago, Diamanti, Michaela A., Müller, Nina, Gamrekelashvili, Jaba, Putoczki, Tracy, Horst, David, Mankan, Arun K., Öner, Meryem G., Müller, Susanna, Müller-Höcker, Josef, Kirchner, Thomas, Slotta-Huspenina, Julia, Taketo, M. Mark, Reinheckel, Thomas, Dröse, Stefan, Larner, Andrew C., Wels, Winfried S., Ernst, Matthias, Greten, Tim F., Arkan, Melek C., Korn, Thomas, Wirth, Dagmar, Greten, Florian R.
Опубликовано в: Cell (2018)