IκBβ is an essential co-activator for LPS-induced IL-1β transcription in vivo

Inhibitor of κB (IκB) β (IκBβ) represents one of the major primary regulators of NF-κB in mammals. In contrast to the defined regulatory interplay between NF-κB and IκBα, much less is known about the biological function of IκBβ. To elucidate the physiological role of IκBβ in NF-κB signaling in vivo,...

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Main Authors: Scheibel, Melanie, Klein, Bettina, Merkle, Heidrun, Schulz, Manon, Fritsch, Ralph, Greten, Florian R., Arkan, Melek C., Schneider, Günter, Schmid, Roland M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989768/
https://ncbi.nlm.nih.gov/pubmed/20975042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100864
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