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Opposing functions of IKKβ during acute and chronic intestinal inflammation

NF-κB is a key transcriptional regulator of inflammatory responses, but also controls expression of prosurvival genes, whose products protect tissues from damage and may thus act indirectly in an antiinflammatory fashion. The variable importance of these two distinct NF-κB-controlled responses impac...

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Bibliografiska uppgifter
Huvudupphovsmän: Eckmann, Lars, Nebelsiek, Tim, Fingerle, Alexander A., Dann, Sara M., Mages, Jörg, Lang, Roland, Robine, Sylvie, Kagnoff, Martin F., Schmid, Roland M., Karin, Michael, Arkan, Melek C., Greten, Florian R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2008
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567492/
https://ncbi.nlm.nih.gov/pubmed/18815378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808216105
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