Integrated analysis of preclinical data to support the design of the first in man study of LY2181308, a second generation antisense oligonucleotide

por Callies, Sophie, André, Valérie, Patel, Bharvin, Waters, David, Francis, Paul, Burgess, Michael, Lahn, Michael
Publicado 2011

Challenging Cosmetic Innovation: The Skin Microbiota and Probiotics Protect the Skin from UV-Induced Damage

por Souak, Djouhar, Barreau, Magalie, Courtois, Aurélie, André, Valérie, Duclairoir Poc, Cécile, Feuilloley, Marc G. J., Gault, Manon
Publicado en Microorganisms (2021)

Cover Image, Volume 52, Issue 1

por de Bengy, Anne‐France, Forraz, Nico, Danoux, Louis, Berthelemy, Nicolas, Cadau, Sébastien, Degoul, Olivier, Andre, Valérie, Pain, Sabine, McGuckin, Colin
Publicado en Cell Prolif (2019)

Development of new 3D human ex vivo models to study sebaceous gland lipid metabolism and modulations

por de Bengy, Anne‐France, Forraz, Nico, Danoux, Louis, Berthelemy, Nicolas, Cadau, Sébastien, Degoul, Olivier, Andre, Valérie, Pain, Sabine, McGuckin, Colin
Publicado en Cell Prolif (2018)

Management of Abemaciclib‐Associated Adverse Events in Patients with Hormone Receptor‐Positive, Human Epidermal Growth Factor Receptor 2‐Negative Advanced Breast Cancer: Safety Ana...

por Rugo, Hope S., Huober, Jens, García‐Sáenz, José A., Masuda, Norikazu, Sohn, Joo Hyuk, Andre, Valerie A.M., Barriga, Susana, Cox, Joanne, Goetz, Matthew
Publicado en Oncologist (2020)

Management of Abemaciclib‐Associated Adverse Events in Patients with Hormone Receptor‐Positive, Human Epidermal Growth Factor Receptor 2‐Negative Advanced Breast Cancer: Safety Ana...

por Rugo, Hope S., Huober, Jens, García‐Sáenz, José A., Masuda, Norikazu, Sohn, Joo Hyuk, Andre, Valerie A.M., Barriga, Susana, Cox, Joanne, Goetz, Matthew
Publicado en Oncologist (2021)

In Reply

por Rugo, Hope S., Huober, Jens, Garcia‐Saenz, Jose A., Masuda, Norikazu, Sohn, Joo Hyuk, Andre, Valerie A.M., Barriga, Susana, Cox, Joanne, Goetz, Matthew
Publicado en Oncologist (2021)

Safety and Pharmacokinetics of the Antisense Oligonucleotide (ASO) LY2181308 as a Single-Agent or in Combination with Idarubicin and Cytarabine in Patients with Refractory or Relap...

por Erba, Harry P., Sayar, Hamid, Juckett, Mark, Lahn, Michael, Andre, Valerie, Callies, Sophie, Schmidt, Shelly, Kadam, Sunil, Brandt, John T., Van Bockstaele, Dirk, Andreeff, Michael
Publicado 2013

Phase I Study of LY2940680, a Smo Antagonist, in Patients with Advanced Cancer Including Treatment-Naïve and Previously Treated Basal Cell Carcinoma

por Bendell, Johanna, Andre, Valerie, Ho, Alan, Kudchadkar, Ragini, Migden, Michael, Infante, Jeffrey, Tiu, Ramon V., Pitou, Celine, Tucker, Trevor, Brail, Les, Hoff, Daniel Von
Publicado en Clin Cancer Res (2018)

Abemaciclib as initial therapy for advanced breast cancer: MONARCH 3 updated results in prognostic subgroups

por Johnston, Stephen, O’Shaughnessy, Joyce, Martin, Miguel, Huober, Jens, Toi, Masakazu, Sohn, Joohyuk, André, Valérie A. M., Martin, Holly R., Hardebeck, Molly C., Goetz, Matthew P.
Publicado en NPJ Breast Cancer (2021)

Health‐Related Quality of Life in MONARCH 2: Abemaciclib plus Fulvestrant in Hormone Receptor‐Positive, HER2‐Negative Advanced Breast Cancer After Endocrine Therapy

por Kaufman, Peter A., Toi, Masakazu, Neven, Patrick, Sohn, Joohyuk, Grischke, Eva‐Maria, Andre, Valerie, Stoffregen, Clemens, Shekarriz, Sarah, Price, Gregory L., Carter, Gebra Cuyun, Sledge, George W.
Publicado en Oncologist (2019)

Health‐Related Quality of Life in MONARCH 3: Abemaciclib plus an Aromatase Inhibitor as Initial Therapy in HR+, HER2− Advanced Breast Cancer

por Goetz, Matthew P., Martin, Miguel, Tokunaga, Eriko, Park, In Hae, Huober, Jens, Toi, Masakazu, Stoffregen, Clemens, Shekarriz, Sarah, Andre, Valerie, Gainford, M. Corona, Price, Gregory L., Johnston, Stephen
Publicado en Oncologist (2020)

Safety and efficacy of abemaciclib plus endocrine therapy in older patients with hormone receptor-positive/human epidermal growth factor receptor 2-negative advanced breast cancer:...

por Goetz, Matthew P., Okera, Meena, Wildiers, Hans, Campone, Mario, Grischke, Eva-Maria, Manso, Luis, André, Valérie A. M., Chouaki, Nadia, San Antonio, Belén, Toi, Masakazu, Sledge, George W.
Publicado en Breast Cancer Res Treat (2021)

Molecular Imaging and Pharmacokinetic Analysis of Carbon-11 Labeled Antisense Oligonucleotide LY2181308 in Cancer Patients

por Saleem, Azeem, Matthews, Julian C., Ranson, Malcolm, Callies, Sophie, André, Valérie, Lahn, Michael, Dickinson, Claire, Prenant, Christian, Brown, Gavin, McMahon, Adam, Talbot, Denis C., Jones, Terry, Price, Patricia M.
Publicado 2011

A Phase 1 Dose-Escalation, Pharmacokinetic, and Pharmacodynamic Evaluation of eIF-4E Antisense Oligonucleotide LY2275796 in Patients with Advanced Cancer

por Hong, David S., Kurzrock, Razelle, Oh, Yun, Wheler, Jennifer, Naing, Aung, Brail, Les, Callies, Sophie, André, Valérie, Kadam, Sunil K, Nasir, Aejaz, Holzer, Timothy R., Meric-Bernstam, Funda, Fishman, Mayer, Simon, George
Publicado en Clin Cancer Res (2011)

Phase 1 study of narnatumab, an anti-RON receptor monoclonal antibody, in patients with advanced solid tumors

por LoRusso, Patricia M., Gounder, Mrinal, Jalal, Shadia I., André, Valérie, Kambhampati, Siva Rama Prasad, Loizos, Nick, Hall, Jennifer, Holzer, Timothy R., Nasir, Aejaz, Cosaert, Jan, Kauh, John, Chiorean, E. Gabriela
Publicado en Invest New Drugs (2017)

Evaluation of Antitumor Activity Using Change in Tumor Size of the Survivin Antisense Oligonucleotide LY2181308 in Combination with Docetaxel for Second-Line Treatment of Patients...

por Natale, Ronald, Blackhall, Fiona, Kowalski, Dariusz, Ramlau, Rodryg, Bepler, Gerold, Grossi, Francesco, Lerchenmüller, Christian, Pinder-Schenck, Mary, Mezger, Jörg, Danson, Sarah, Gadgeel, Shirish M., Summers, Yvonne, Callies, Sophie, André, Valérie, Das, Mayukh, Lahn, Michael, Talbot, Denis
Publicado en J Thorac Oncol (2014)

Cinquante nuances de rose. Les affinités électives du prince de Ligne

por Acke, Daniel, Bernard, Bruno, André, Valérie, Brix, Michel, Cerman, Ivo, Chaouche, Sabine, Colson, Bruno, Cornaz, Marie, Couvreur, Manuel, Guri, Shipé, de Harlez de Deulin, Nathalie, Loir, Christophe, Mouriau de Meulenacker, Pierre, Speeckaert, Jean-Charles, Preyat, Fabrice
Publicado en Études sur le XVIIIe siècle (2018)

Abemaciclib in combination with endocrine therapy for East Asian patients with HR+, HER2− advanced breast cancer: MONARCH 2 & 3 trials

por Toi, Masakazu, Inoue, Kenichi, Masuda, Norikazu, Iwata, Hiroji, Sohn, Joohyuk, Hae Park, In, Im, Seock‐Ah, Chen, Shin‐Cheh, Enatsu, Sotaro, Turner, P. Kellie, André, Valérie A. M., Hardebeck, Molly C., Sakaguchi, Sachi, Goetz, Matthew P., Sledge, George W.
Publicado en Cancer Sci (2021)

Dose study of the multikinase inhibitor, LY2457546, in patients with relapsed acute myeloid leukemia to assess safety, pharmacokinetics, and pharmacodynamics

por Wacheck, Volker, Lahn, Michael, Dickinson, Gemma, Füreder, Wolfgang, Meyer, Renata, Herndlhofer, Susanne, Füreder, Thorsten, Dorfner, Georg, Pillay, Sada, André, Valérie, Burkholder, Timothy P, Akunda, Jacqueline K, Flye-Blakemore, Leann, Van Bockstaele, Dirk, Schlenk, Richard F, Sperr, Wolfgang R, Valent, Peter
Publicado 2011