Novel AAV-Based Rat Model of Forebrain Synucleinopathy Shows Extensive Pathologies and Progressive Loss of Cholinergic Interneurons

Autor Aldrin-Kirk, Patrick, Davidsson, Marcus, Holmqvist, Staffan, Li, Jia-Yi, Björklund, Tomas
Vydáno 2014

DREADD Modulation of Transplanted DA Neurons Reveals a Novel Parkinsonian Dyskinesia Mechanism Mediated by the Serotonin 5-HT6 Receptor

Autor Aldrin-Kirk, Patrick, Heuer, Andreas, Wang, Gang, Mattsson, Bengt, Lundblad, Martin, Parmar, Malin, Björklund, Tomas
Vydáno v Neuron (2016)

A systematic capsid evolution approach performed in vivo for the design of AAV vectors with tailored properties and tropism

Autor Davidsson, Marcus, Wang, Gang, Aldrin-Kirk, Patrick, Cardoso, Tiago, Nolbrant, Sara, Hartnor, Morgan, Mudannayake, Janitha, Parmar, Malin, Björklund, Tomas
Vydáno v Proc Natl Acad Sci U S A (2019)

Molecular barcoding of viral vectors enables mapping and optimization of mRNA trans-splicing

Autor Davidsson, Marcus, Díaz-Fernández, Paula, Torroba, Marcos, Schwich, Oliver D., Aldrin-Kirk, Patrick, Quintino, Luis, Heuer, Andreas, Wang, Gang, Lundberg, Cecilia, Björklund, Tomas
Vydáno v RNA (2018)

Modelling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient

Autor Rifes, Pedro, Isaksson, Marc, Rathore, Gaurav Singh, Aldrin-Kirk, Patrick, Møller, Oliver Knights, Barzaghi, Guido, Lee, Julie, Egerod, Kristoffer Lihme, Rausch, Dylan Matthew, Parmar, Malin, Pers, Tune H., Laurell, Thomas, Kirkeby, Agnete
Vydáno v Nat Biotechnol (2020)

A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency

Autor Tordo, Julie, O’Leary, Claire, Antunes, André S L M, Palomar, Nuria, Aldrin-Kirk, Patrick, Basche, Mark, Bennett, Antonette, D’Souza, Zelpha, Gleitz, Hélène, Godwin, Annie, Holley, Rebecca J, Parker, Helen, Liao, Ai Yin, Rouse, Paul, Youshani, Amir Saam, Dridi, Larbi, Martins, Carla, Levade, Thierry, Stacey, Kevin B, Davis, Daniel M, Dyer, Adam, Clément, Nathalie, Björklund, Tomas, Ali, Robin R, Agbandje-McKenna, Mavis, Rahim, Ahad A, Pshezhetsky, Alexey, Waddington, Simon N, Linden, R Michael, Bigger, Brian W, Henckaerts, Els
Vydáno v Brain (2018)