Current Pathological and Laboratory Considerations in the Diagnosis of Disseminated Intravascular Coagulation

por Toh, Cheng-Hock, Alhamdi, Yasir, Abrams, Simon T.
Publicado en Ann Lab Med (2016)

Histone-associated thrombocytopenia in critically ill patients

por Alhamdi, Yasir, Abrams, Simon T, Lane, Steven, Wang, Guozheng, Toh, Cheng-Hock
Publicado en JAMA (2016)

Granulocyte colony-stimulating factor (G-CSF) increases histone-complexed DNA plasma levels in healthy volunteers

por Schoergenhofer, Christian, Schwameis, Michael, Wohlfarth, Philipp, Brostjan, Christine, Abrams, Simon T., Toh, Cheng-Hock, Jilma, Bernd
Publicado en Clin Exp Med (2016)

A Novel Assay for Neutrophil Extracellular Trap Formation Independently Predicts Disseminated Intravascular Coagulation and Mortality in Critically Ill Patients

por Abrams, Simon T., Morton, Ben, Alhamdi, Yasir, Alsabani, Mohmad, Lane, Steven, Welters, Ingeborg D., Wang, Guozheng, Toh, Cheng-Hock
Publicado en Am J Respir Crit Care Med (2019)

A novel assay of neutrophil extracellular trap (NET) formation identifies anti-IL-8 therapies to reduce disseminated intravascular coagulation and mortality in the intensive care u...

por Abrams, Simon, Morton, Ben, Alhamdi, Yasir, Alsabani, Mohmad, Cheng, Zhenxing, Lane, Steven, Welters, Ingeborg, Wang, Guozheng, Toh, Cheng-Hock
Publicado en Clin Med (Lond) (2020)

The Critical Roles and Mechanisms of Immune Cell Death in Sepsis

por Cheng, Zhenxing, Abrams, Simon T., Toh, Julien, Wang, Susan Siyu, Wang, Zhi, Yu, Qian, Yu, Weiping, Toh, Cheng-Hock, Wang, Guozheng
Publicado en Front Immunol (2020)

Circulating Pneumolysin Is a Potent Inducer of Cardiac Injury during Pneumococcal Infection

por Alhamdi, Yasir, Neill, Daniel R., Abrams, Simon T., Malak, Hesham A., Yahya, Reham, Barrett-Jolley, Richard, Wang, Guozheng, Kadioglu, Aras, Toh, Cheng-Hock
Publicado en PLoS Pathog (2015)

The Central Role and Possible Mechanisms of Bacterial DNAs in Sepsis Development

por Cheng, Zhenxing, Abrams, Simon T., Austin, James, Toh, Julien, Wang, Susan Siyu, Wang, Zhi, Yu, Qian, Yu, Weiping, Toh, Cheng Hock, Wang, Guozheng
Publicado en Mediators Inflamm (2020)

Circulating Histones Are Mediators of Trauma-associated Lung Injury

por Abrams, Simon T., Zhang, Nan, Manson, Joanna, Liu, Tingting, Dart, Caroline, Baluwa, Florence, Wang, Susan Siyu, Brohi, Karim, Kipar, Anja, Yu, Weiping, Wang, Guozheng, Toh, Cheng-Hock
Publicado 2013

Extracellular histones stimulate collagen expression in vitro and promote liver fibrogenesis in a mouse model via the TLR4-MyD88 signaling pathway

por Wang, Zhi, Cheng, Zhen-Xing, Abrams, Simon T, Lin, Zi-Qi, Yates, ED, Yu, Qian, Yu, Wei-Ping, Chen, Ping-Sheng, Toh, Cheng-Hock, Wang, Guo-Zheng
Publicado en World J Gastroenterol (2020)

Parasite histones mediate blood–brain barrier disruption in cerebral malaria

por Moxon, Christopher, Alhamdi, Yasir, Storm, Janet, Toh, Julien, Ko, Joo Yeon, Murphy, George, Taylor, Terrie, Seydel, Karl, Wang, Guozheng, García-Car, Guillermo, Molyneux, Malcolm, Craig, Alister, Abrams, Simon, Toh, Cheng-Hock
Publicado en Clin Med (Lond) (2020)

Parasite histones are toxic to brain endothelium and link blood barrier breakdown and thrombosis in cerebral malaria

por Moxon, Christopher A., Alhamdi, Yasir, Storm, Janet, Toh, Julien M. H., McGuinness, Dagmara, Ko, Joo Yeon, Murphy, George, Lane, Steven, Taylor, Terrie E., Seydel, Karl B., Kampondeni, Sam, Potchen, Michael, O’Donnell, James S., O’Regan, Niamh, Wang, Guozheng, García-Cardeña, Guillermo, Molyneux, Malcolm, Craig, Alister G., Abrams, Simon T., Toh, Cheng-Hock
Publicado en Blood Adv (2020)

Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19

por Thwaites, Ryan S, Sanchez Sevilla Uruchurtu, Ashley, Siggins, Matthew K, Liew, Felicity, Russell, Clark D, Moore, Shona C, Fairfield, Cameron, Carter, Edwin, Abrams, Simon, Short, Charlotte-Eve, Thaventhiran, Thilipan, Bergstrom, Emma, Gardener, Zoe, Ascough, Stephanie, Chiu, Christopher, Docherty, Annemarie B, Hunt, David, Crow, Yanick J, Solomon, Tom, Taylor, Graham P, Turtle, Lance, Harrison, Ewen M, Dunning, Jake, Semple, Malcolm G, Baillie, J Kenneth, Openshaw, Peter JM
Publicado en Sci Immunol (2021)