The Central Role and Possible Mechanisms of Bacterial DNAs in Sepsis Development

The pathological roles of bacterial DNA have been documented many decades ago. Bacterial DNAs are different from mammalian DNAs; the latter are heavily methylated. Mammalian cells have sensors such as TLR-9 to sense the DNAs with nonmethylated CpGs and distinguish them from host DNAs with methylated...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Cheng, Zhenxing, Abrams, Simon T., Austin, James, Toh, Julien, Wang, Susan Siyu, Wang, Zhi, Yu, Qian, Yu, Weiping, Toh, Cheng Hock, Wang, Guozheng
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479481/
https://ncbi.nlm.nih.gov/pubmed/32934605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/7418342
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