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The Central Role and Possible Mechanisms of Bacterial DNAs in Sepsis Development

The pathological roles of bacterial DNA have been documented many decades ago. Bacterial DNAs are different from mammalian DNAs; the latter are heavily methylated. Mammalian cells have sensors such as TLR-9 to sense the DNAs with nonmethylated CpGs and distinguish them from host DNAs with methylated...

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Bibliografiske detaljer
Udgivet i:Mediators Inflamm
Main Authors: Cheng, Zhenxing, Abrams, Simon T., Austin, James, Toh, Julien, Wang, Susan Siyu, Wang, Zhi, Yu, Qian, Yu, Weiping, Toh, Cheng Hock, Wang, Guozheng
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479481/
https://ncbi.nlm.nih.gov/pubmed/32934605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/7418342
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