The Pneumococcal Polysaccharide Capsule and Pneumolysin Differentially Affect CXCL8 and IL-6 Release from Cells of the Upper and Lower Respiratory Tract

von Küng, Eliane, Coward, William R., Neill, Daniel R., Malak, Hesham A., Mühlemann, Kathrin, Kadioglu, Aras, Hilty, Markus, Hathaway, Lucy J.
Veröffentlicht 2014

Circulating Pneumolysin Is a Potent Inducer of Cardiac Injury during Pneumococcal Infection

von Alhamdi, Yasir, Neill, Daniel R., Abrams, Simon T., Malak, Hesham A., Yahya, Reham, Barrett-Jolley, Richard, Wang, Guozheng, Kadioglu, Aras, Toh, Cheng-Hock
Veröffentlicht in PLoS Pathog (2015)

Neutrophil IL-1β processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation, and is dependent on K(+) efflux

von Karmakar, Mausita, Katsnelson, Michael, Malak, Hesham A., Greene, Neil G., Howell, Scott J., Hise, Amy G., Camilli, Andrew, Kadioglu, Aras, Dubyak, George R., Pearlman, Eric
Veröffentlicht in J Immunol (2015)