Synthesis of 1,4-imino-L-lyxitols modified at C-5 and their evaluation as inhibitors of GH38 α-mannosidases

por Bella, Maroš, Šesták, Sergej, Moncoľ, Ján, Koóš, Miroslav, Poláková, Monika
Publicado en Beilstein J Org Chem (2018)

1,4-Dideoxy-1,4-imino-d-lyxitols and L-lyxitols may bind to Golgi α-mannosidase II in a different protonation form

por Kóňa, Juraj, Šesták, Sergej, Wilson, Iain B.H., Poláková, Monika
Publicado en Org Biomol Chem (2022)

‘Click chemistry‘ synthesis of 1-(α-d-mannopyranosyl)-1,2,3-triazoles for inhibition of α-mannosidases

por Poláková, Monika, Stanton, Rhiannon, Wilson, Iain B. H., Holková, Ivana, Šesták, Sergej, Machová, Eva, Jandová, Zuzana, Kóňa, Juraj
Publicado en Carbohydr Res (2015)

Bypass of Activation Loop Phosphorylation by Aspartate 836 in Activation of the Endoribonuclease Activity of Ire1

por Armstrong, Michael C., Šestak, Sergej, Ali, Ahmed A., Sagini, Hanan A. M., Brown, Max, Baty, Karen, Treumann, Achim, Schröder, Martin
Publicado en Mol Cell Biol (2017)

N-Benzyl substitution of polyhydroxypyrrolidines - the way to selective inhibitors of Golgi α-mannosidase II

por Šesták, Sergej, Bella, Maroš, Klunda, Tomáš, Gurská, Soňa, Džubák, Petr, Wöls, Florian, Wilson, Iain B. H., Sladek, Vladimir, Hajdúch, Marián, Poláková, Monika, Kóňa, Juraj
Publicado en ChemMedChem (2018)