High performance CHO cell line development platform for enhanced production of recombinant proteins including difficult-to-express proteins

Por Girod, Pierre-Alain, Le Fourn, Valérie, Calabrese, David, Regamey, Alexandre, Ley, Deborah, Mermod, Nicolas
Publicado em 2013

The Tumor Suppressor CYLD Interacts with TRIP and Regulates Negatively Nuclear Factor κB Activation by Tumor Necrosis Factor

Por Regamey, Alexandre, Hohl, Daniel, Liu, Jia Wei, Roger, Thierry, Kogerman, Priit, Toftgård, Rune, Huber, Marcel
Publicado em 2003

Overexpression of transcription factor Foxa1 and target genes remediate therapeutic protein production bottlenecks in Chinese hamster ovary cells

Por Berger, Audrey, Le Fourn, Valérie, Masternak, Jacqueline, Regamey, Alexandre, Bodenmann, Iris, Girod, Pierre‐Alain, Mermod, Nicolas
Publicado no Biotechnol Bioeng (2020)

Influence of cytoskeleton organization on recombinant protein expression by CHO cells

Por Pourcel, Lucille, Buron, Flavien, Arib, Ghislaine, Le Fourn, Valérie, Regamey, Alexandre, Bodenmann, Iris, Girod, Pierre‐Alain, Mermod, Nicolas
Publicado no Biotechnol Bioeng (2020)

MAR Elements and Transposons for Improved Transgene Integration and Expression

Por Ley, Déborah, Harraghy, Niamh, Le Fourn, Valérie, Bire, Solenne, Girod, Pierre-Alain, Regamey, Alexandre, Rouleux-Bonnin, Florence, Bigot, Yves, Mermod, Nicolas
Publicado em 2013

MAR‐Mediated transgene integration into permissive chromatin and increased expression by recombination pathway engineering

Por Kostyrko, Kaja, Neuenschwander, Samuel, Junier, Thomas, Regamey, Alexandre, Iseli, Christian, Schmid‐Siegert, Emanuel, Bosshard, Sandra, Majocchi, Stefano, Le Fourn, Valérie, Girod, Pierre‐Alain, Xenarios, Ioannis, Mermod, Nicolas
Publicado no Biotechnol Bioeng (2016)