The Tumor Suppressor CYLD Interacts with TRIP and Regulates Negatively Nuclear Factor κB Activation by Tumor Necrosis Factor

Cylindromas are benign adnexal skin tumors caused by germline mutations in the CYLD gene. In most cases the second wild-type allele is lost in tumor tissue, suggesting that CYLD functions as tumor suppressor. CYLD is a protein of 956 amino acids harboring a functional deubiquitinating domain at the...

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Detalhes bibliográficos
Main Authors: Regamey, Alexandre, Hohl, Daniel, Liu, Jia Wei, Roger, Thierry, Kogerman, Priit, Toftgård, Rune, Huber, Marcel
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194148/
https://ncbi.nlm.nih.gov/pubmed/14676304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031187
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