Microbial esterases and ester prodrugs: An unlikely marriage for combatting antibiotic resistance

Por Larsen, Erik M., Johnson, R. Jeremy
Publicado no Drug Dev Res (2018)

Conformation-Activity Relationships of Polyketide Natural Products

Por Larsen, Erik M., Wilson, Matthew R., Taylor, Richard E.
Publicado no Nat Prod Rep (2015)

Conformational Preferences of Zampanolide and Dactylolide

Por Larsen, Erik M., Wilson, Matthew R., Zajicek, Jaroslav, Taylor, Richard E.
Publicado em 2013

Ester-prodrugs of ethambutol control its antibacterial activity and provide rapid screening for mycobacterial hydrolase activity

Por Larsen, Erik M., Stephens, Dominique C., Clarke, Nathan H., Johnson, R. Jeremy
Publicado no Bioorg Med Chem Lett (2017)

In vivo delivery and activation of masked fluorogenic hydrolase substrates by endogenous hydrolases in C. elegans

Por Dube, Shataakshi, Dube, Hitesh, Green, Nicole B., Larsen, Erik M., White, Alex, Johnson, R. Jeremy, Kowalski, Jennifer R.
Publicado no Chembiochem (2017)

Fluorogenic structure activity library pinpoints molecular variations in substrate specificity of structurally homologous esterases

Por White, Alex, Koelper, Andrew, Russell, Arielle, Larsen, Erik M., Kim, Charles, Lavis, Luke D., Hoops, Geoffrey C., Johnson, R. Jeremy
Publicado no J Biol Chem (2018)

Measuring the global substrate specificity of mycobacterial serine hydrolases using a library of fluorogenic ester substrates

Por Bassett, Braden, Waibel, Brent, White, Alex, Hansen, Heather, Stephens, Dominique, Koelper, Andrew, Larsen, Erik M., Kim, Charles, Glanzer, Adam, Lavis, Luke D., Hoops, Geoffrey C., Johnson, R. Jeremy
Publicado no ACS Infect Dis (2018)