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Conformation-Activity Relationships of Polyketide Natural Products

Polyketides represent an important class of secondary metabolites that interact with biological targets connected to a variety of disease-associated pathways. Remarkably, nature’s assembly lines, polyketide synthases, manufacture these privileged structures through a combinatorial mixture of just a...

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Detalles Bibliográficos
Publicado en:Nat Prod Rep
Main Authors: Larsen, Erik M., Wilson, Matthew R., Taylor, Richard E.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4443481/
https://ncbi.nlm.nih.gov/pubmed/25974024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5np00014a
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