Neoadjuvant Hypofractionated Radiotherapy and Chemotherapy in High-Grade Extremity Soft Tissue Sarcomas: Phase 2 Clinical Trial Protocol

Por Spencer, Ranyell MSB, Aguiar Junior, Samuel, Ferreira, Fabio O, Stevanato Filho, Paulo R, Kupper, Bruna EC, Silva, Maria LG, Mello, Celso A, Bezerra, Tiago S, Lopes, Ademar
Publicado no JMIR Res Protoc (2017)

Prospective phase-II-study evaluating postoperative radiotherapy of cervical and endometrial cancer patients using protons – the APROVE-trial

Por Arians, N., Lindel, K., Krisam, J., Herfarth, K., Krug, D., Akbaba, S., Oelmann-Avendano, J., Debus, J.
Publicado no Radiat Oncol (2017)

Updated survival analysis of a randomized phase III study of subcutaneous versus intravenous bortezomib in patients with relapsed multiple myeloma

Por Arnulf, Bertrand, Pylypenko, Halyna, Grosicki, Sebastian, Karamanesht, Ievgenii, Leleu, Xavier, van de Velde, Helgi, Feng, Huaibao, Cakana, Andrew, Deraedt, William, Moreau, Philippe
Publicado em 2012

Phase II study of capecitabine plus oxaliplatin (CapOX) as adjuvant chemotherapy for locally advanced rectal cancer (CORONA II)

Por Hattori, Norifumi, Nakayama, Goro, Uehara, Keisuke, Aiba, Toshisada, Ishigure, Kiyoshi, Sakamoto, Eiji, Tojima, Yuichiro, Kanda, Mitsuro, Kobayashi, Daisuke, Tanaka, Chie, Yamada, Suguru, Koike, Masahiko, Fujiwara, Michitaka, Nagino, Masato, Kodera, Yasuhiro
Publicado no Int J Clin Oncol (2019)

A Phase 2 Trial of Regorafenib as a Single Agent in Patients with Chemotherapy Refractory Advanced and Metastatic Biliary Tract Adenocarcinoma

Por Sun, Weijing, Patel, Anuj, Normolle, Daniel, Patel, Krishna, Ohr, James, Lee, James J., Bahary, Nathan, Chu, Edward, Streeter, Natalie, Drummond, Summer
Publicado no Cancer (2018)

A phase II randomized trial of induction chemotherapy versus no induction chemotherapy followed...

Por Ajani, J. A., Xiao, L., Roth, J. A., Hofstetter, W. L., Walsh, G., Komaki, R., Liao, Z., Rice, D. C., Vaporciyan, A. A., Maru, D. M., Lee, J. H., Bhutani, M. S., Eid, A., Yao, J. C., Phan, A. P., Halpin, A., Suzuki, A., Taketa, T., Thall, P. F., Swisher, S. G.
Publicado em 2013

Randomised phase II trial of docetaxel and sunitinib in patients with metastatic gastric cancer who were previously treated with fluoropyrimidine and platinum

Por Yi, J H, Lee, J, Lee, J, Park, S H, Park, J O, Yim, D-S, Park, Y S, Lim, H Y, Kang, W K
Publicado em 2012

A phase II randomised (calibrated design) study on the activity of the single-agent trabectedin in metastatic or locally relapsed uterine leiomyosarcoma

Por Gadducci, Angiolo, Grosso, Federica, Scambia, Giovanni, Raspagliesi, Francesco, Colombo, Nicoletta, Grignani, Giovanni, Casali, Paolo, Sanfilippo, Roberta, Buonadonna, Angela, Santoro, Armando, Bruzzone, Milena, Artioli, Grazia, Lorusso, Domenica, Biagioli, Elena, Fossati, Roldano, Galli, Francesca, Negri, Emanuele, Rulli, Eliana, Torri, Valter, D’Incalci, Maurizio
Publicado no Br J Cancer (2018)

Phase II study of reintroduction of oxaliplatin for advanced colorectal cancer in patients previously treated with oxaliplatin and irinotecan: RE-OPEN study

Por Suenaga, Mitsukuni, Mizunuma, Nobuyuki, Matsusaka, Satoshi, Shinozaki, Eiji, Ozaka, Masato, Ogura, Mariko, Yamaguchi, Toshiharu
Publicado no Drug Des Devel Ther (2015)

Clinical activity of patupilone in patients with pretreated advanced/metastatic colon cancer: results of a phase I dose escalation trial

Por Melichar, B, Casado, E, Bridgewater, J, Bennouna, J, Campone, M, Vitek, P, Delord, J-P, Cerman, J, Salazar, R, Dvorak, J, Sguotti, C, Urban, P, Viraswami-Appanna, K, Tan, E, Tabernero, J
Publicado em 2011

471. Safety and Efficacy of Oral and/or Intravenous Tedizolid Phosphate (TZD) in Adolescents...

Por Bradley, John S, Antadze, Tinatin, Mitha, Ismail H, Ninov, Borislav, Tayob, Mohammed S, Broyde, Natasha, Butterton, Joan R, Chou, Margaret Z, De Anda, Carisa S, Kim, Jason Y, Sears, Pamela S
Publicado no Open Forum Infect Dis (2019)

SIMPLIFY-1: A Phase III Randomized Trial of Momelotinib Versus Ruxolitinib in Janus Kinase Inhibitor–Naïve Patients With Myelofibrosis

Por Mesa, Ruben A., Kiladjian, Jean-Jacques, Catalano, John V., Devos, Timothy, Egyed, Miklos, Hellmann, Andrzei, McLornan, Donal, Shimoda, Kazuya, Winton, Elliott F., Deng, Wei, Dubowy, Ronald L., Maltzman, Julia D., Cervantes, Francisco, Gotlib, Jason
Publicado no J Clin Oncol (2017)

A Randomized, Open-Label, Phase II Study Comparing Pemetrexed Plus Cisplatin Followed...

Por Yoo, Kwai Han, Lee, Su Jin, Cho, Jinhyun, Lee, Ki Hyeong, Park, Keon Uk, Kim, Ki Hwan, Cho, Eun Kyung, Choi, Yoon Hee, Kim, Hye Ryun, Kim, Hoon-Gu, Ahn, Heui June, Lee, Ha Yeon, Yun, Hwan Jung, Kang, Jin-Hyoung, Jeong, Jaeheon, Choi, Moon Young, Jung, Sin-Ho, Sun, Jong-Mu, Lee, Se-Hoon, Ahn, Jin Seok, Park, Keunchil, Ahn, Myung-Ju
Publicado no Cancer Res Treat (2019)

NRG Oncology RTOG 0625: A Randomized Phase II Trial of Bevacizumab with either Irinotecan or Dose-Dense Temozolomide in Recurrent Glioblastoma

Por Gilbert, Mark R., Pugh, Stephanie L, Aldape, Ken, Sorensen, A. Gregory, Mikkelsen, Tom, Penas-Prado, Marta, Bukshstein, Felix, Kwok, Young, Lee, R. Jeffrey, Mehta, Minesh
Publicado no J Neurooncol (2016)

Randomized phase II trial of hypofractionated proton versus carbon ion radiation therapy in patients with sacrococcygeal chordoma-the ISAC trial protocol

Por Uhl, Matthias, Edler, Lutz, Jensen, Alexandra D, Habl, Gregor, Oelmann, Jan, Röder, Falk, Jäckel, Oliver, Debus, Jürgen, Herfarth, Klaus
Publicado em 2014

BACCHUS: A randomised non-comparative phase II study of neoadjuvant chemotherapy (NACT) in patients with locally advanced rectal cancer (LARC)

Por Glynne-Jones, R., Hall, M.R., Lopes, A., Pearce, S., Goh, V., Bosompem, S., Bridgewater, J., Chau, I., Wasan, H., Moran, B., Melcher, L., West, N.P., Quirke, P., Wong, W.-L., Beare, S., Hava, N., Duggan, M., Harrison, M.
Publicado no Heliyon (2018)

Caveolin-1 expression predicts efficacy of weekly nab-paclitaxel plus gemcitabine for metastatic breast cancer in the phase II clinical trial

Por Zhao, Yannan, Lv, Fangfang, Chen, She, Wang, Zhonghua, Zhang, Jian, Zhang, Sheng, Cao, Jun, Wang, Leiping, Cao, Enying, Wang, Biyun, Hu, Xichun
Publicado no BMC Cancer (2018)

Individualized Adaptive Stereotactic Body Radiotherapy for Liver Tumors in Patients at High Risk for Liver Damage: A Phase 2 Clinical Trial

Por Feng, Mary, Suresh, Krithika, Schipper, Matthew J., Bazzi, Latifa, Ben-Josef, Edgar, Matuszak, Martha M., Parikh, Neehar D., Welling, Theodore H., Normolle, Daniel, Ten Haken, Randall K., Lawrence, Theodore S.
Publicado no JAMA Oncol (2017)

Phase II multicentre randomised study of docetaxel plus epirubicin vs 5-fluorouracil plus epirubicin and cyclophosphamide in metastatic breast cancer

Por Bonneterre, J, Dieras, V, Tubiana-Hulin, M, Bougnoux, P, Bonneterre, M-E, Delozier, T, Mayer, F, Culine, S, Dohoulou, N, Bendahmane, B
Publicado em 2004

A phase II trial of panobinostat in patients with advanced pretreated soft tissue sarcoma. A study from the French Sarcoma Group

Por Cassier, P A, Lefranc, A, Y Amela, E, Chevreau, C, Bui, B N, Lecesne, A, Ray-Coquard, I, Chabaud, S, Penel, N, Berge, Y, Dômont, J, Italiano, A, Duffaud, F, Cadore, A-C, Polivka, V, Blay, J-Y
Publicado em 2013