A phase II trial of panobinostat in patients with advanced pretreated soft tissue sarcoma. A study from the French Sarcoma Group

BACKGROUND: Soft tissue sarcomas (STS) are rare tumours for which treatment options are limited in the advanced setting. Histone deacetylase inhibitors have shown activity in preclinical models of STS. METHODS: We conducted a single-arm, open-label, multicentre phase II study to assess the efficacy...

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Hlavní autoři: Cassier, P A, Lefranc, A, Y Amela, E, Chevreau, C, Bui, B N, Lecesne, A, Ray-Coquard, I, Chabaud, S, Penel, N, Berge, Y, Dômont, J, Italiano, A, Duffaud, F, Cadore, A-C, Polivka, V, Blay, J-Y
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
Témata:
Clinical Study
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749588/
https://ncbi.nlm.nih.gov/pubmed/23922114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.442
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