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Aplidin in patients with advanced dedifferentiated liposarcomas: a French Sarcoma Group Single-Arm Phase II study
BACKGROUND: Preclinical data have suggested a therapeutic role of JUN pathway activation in dedifferentiated liposarcoma (DDLPS) tumorigenesis. Aplidin(®) is a drug inducing apoptosis through a strong, sustained activation of c-Jun NH2-terminal kinase. METHODS: This phase II trial included patients...
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| Publicado no: | Ann Oncol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4478976/ https://ncbi.nlm.nih.gov/pubmed/26041763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdv195 |
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