Neoadjuvant Hypofractionated Radiotherapy and Chemotherapy in High-Grade Extremity Soft Tissue Sarcomas: Phase 2 Clinical Trial Protocol

BACKGROUND: Neoadjuvant radiotherapy (RT) and chemotherapy are applied to large, high-grade extremity soft tissue sarcomas to treat metastatic disease earlier and sterilize margins to perform R0 surgery. However, preoperative RT increases wound complication rates (rWC), delaying adjuvant chemotherap...

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Detalhes bibliográficos
Publicado no:JMIR Res Protoc
Main Authors: Spencer, Ranyell MSB, Aguiar Junior, Samuel, Ferreira, Fabio O, Stevanato Filho, Paulo R, Kupper, Bruna EC, Silva, Maria LG, Mello, Celso A, Bezerra, Tiago S, Lopes, Ademar
Formato: Artigo
Idioma:Inglês
Publicado em: JMIR Publications 2017
Assuntos:
Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465377/
https://ncbi.nlm.nih.gov/pubmed/28546135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2196/resprot.6806
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