Development of dual delivery antituberculotic system containing rifapentine microspheres and adipose stem cells seeded in hydroxyapatite/tricalcium phosphate

Por Liang, Qiuzhen, Song, Xinghua, She, Shengli, Wang, Zhen, Wang, Chong, Jiang, Dawei
Publicado no Drug Des Devel Ther (2019)

Characterization and evaluation of amine-modified graphene amphotericin B for the treatment of visceral leishmaniasis: in vivo and in vitro studies

Por Mudavath, Shyam Lal, Talat, Mahe, Rai, Madhukar, Srivastava, Onkar Nath, Sundar, Shyam
Publicado em 2014

Design of an epitope-based peptide vaccine against spike protein of human coronavirus: an in silico approach

Por Oany, Arafat Rahman, Emran, Abdullah-Al, Jyoti, Tahmina Pervin
Publicado em 2014

An optimized probucol microencapsulated formulation integrating a secondary bile acid (deoxycholic acid) as a permeation enhancer

Por Mooranian, Armin, Negrulj, Rebecca, Chen-Tan, Nigel, Watts, Gerald F, Arfuso, Frank, Al-Salami, Hani
Publicado em 2014

Preparation, characterization, and in vivo study of rhein-loaded poly(lactic-co-glycolic acid) nanoparticles for oral delivery

Por Yuan, Zheng, Gu, Xinhua
Publicado no Drug Des Devel Ther (2015)

Andrographolide inhibits growth of human T-cell acute lymphoblastic leukemia Jurkat cells by downregulation of PI3K/AKT and upregulation of p38 MAPK pathways

Por Yang, Tingfang, Yao, Shuluan, Zhang, Xianfeng, Guo, Yan
Publicado no Drug Des Devel Ther (2016)

Past and current perspective on new therapeutic targets for Type-II diabetes

Por Patil, Pradip D, Mahajan, Umesh B, Patil, Kalpesh R, Chaudhari, Sandip, Patil, Chandragouda R, Agrawal, Yogeeta O, Ojha, Shreesh, Goyal, Sameer N
Publicado no Drug Des Devel Ther (2017)

In vivo study of doxorubicin-loaded cell-penetrating peptide-modified pH-sensitive liposomes: biocompatibility, bio-distribution, and pharmacodynamics in BALB/c nude mice bearing h...

Por Ding, Yuan, Cui, Wei, Sun, Dan, Wang, Gui-Ling, Hei, Yu, Meng, Shuai, Chen, Jian-Hua, Xie, Ying, Wang, Zhi-Qiang
Publicado no Drug Des Devel Ther (2017)

The oral bioavailability, excretion and cytochrome P450 inhibition properties of epiberberine: an in vivo and in vitro evaluation

Por Chen, Ning, Yang, Xiao-yan, Guo, Chang-e, Bi, Xin-ning, Chen, Jian-hua, Chen, Hong-ying, Li, Hong-pin, Lin, Hong-ying, Zhang, Yu-jie
Publicado no Drug Des Devel Ther (2017)

Development and validation of an oxygen dissociation assay, a screening platform for discovering, and characterizing hemoglobin–oxygen affinity modifiers

Por Patel, Mira P, Siu, Vincent, Silva-Garcia, Abel, Xu, Qing, Li, Zhe, Oksenberg, Donna
Publicado no Drug Des Devel Ther (2018)

Transportan-derived cell-penetrating peptide delivers siRNA to inhibit replication of influenza virus in vivo

Por Zhang, Cuiling, Ren, Weigang, Liu, Qingxin, Tan, Zhikai, Li, Junwei, Tong, Chunyi
Publicado no Drug Des Devel Ther (2019)

miR- 26a Sensitizes Melanoma Cells To Dabrafenib Via Targeting HMGB1-Dependent Autophagy Pathways

Por Yu, Yan, Xiang, Niu, Lin, Min, Huang, Jin-Wen, Zhang, Jing, Cheng, Bo, Ji, Chao
Publicado no Drug Des Devel Ther (2019)

Anti-Tumor Xanthones from Garcinia nujiangensis Suppress Proliferation, and Induce Apoptosis via PARP, PI3K/AKT/mTOR, and MAPK/ERK Signaling Pathways in Human Ovarian Cancers Cells

Por Tang, Zhongyan, Lu, Lihua, Xia, Zhengxiang
Publicado no Drug Des Devel Ther (2020)

Effect of renal function on the pharmacokinetics of fimasartan: a single-dose, open-label, Phase I study

Por Kim, Seokuee, Lee, Jongtae, Shin, Donghoon, Lim, Kyoung Soo, Kim, Yon Su, Jang, In-Jin, Yu, Kyung-Sang
Publicado em 2014

Evaluation of ceftiofur–PHBV microparticles in rats

Por Vilos, Cristian, Constandil, Luis, Rodas, Paula I, Cantin, Mario, Zepeda, Katherine, Herrera, Natalia, Velasquez, Luis A
Publicado em 2014

Design, synthesis, and antitumor evaluation of histone deacetylase inhibitors with l-phenylglycine scaffold

Por Zhang, Yingjie, Li, Xiaoguang, Hou, Jinning, Huang, Yongxue, Xu, Wenfang
Publicado no Drug Des Devel Ther (2015)

Design, synthesis, and antihypertensive activity of curcumin-inspired compounds via ACE inhibition and vasodilation, along with a bioavailability study for possible benefit in card...

Por Zhuang, Xiao-dong, Liao, Li-zhen, Dong, Xiao-bian, Hu, Xun, Guo, Yue, Du, Zhi-min, Liao, Xin-xue, Wang, Li-chun
Publicado no Drug Des Devel Ther (2016)

Selective CDK7 inhibition with BS-181 suppresses cell proliferation and induces cell cycle arrest and apoptosis in gastric cancer

Por Wang, Bo-Yong, Liu, Quan-Yan, Cao, Jun, Chen, Ji-Wei, Liu, Zhi-Su
Publicado no Drug Des Devel Ther (2016)

Synthesis and antimicrobial activity of chiral quaternary N-spiro ammonium bromides with 3′,4′-dihydro-1′H-spiro[isoindoline-2,2′-isoquinoline] skeleton

Por Bielawski, Krzysztof, Leszczyńska, Katarzyna, Kałuża, Zbigniew, Bielawska, Anna, Michalak, Olga, Daniluk, Tamara, Staszewska-Krajewska, Olga, Czajkowska, Anna, Pawłowska, Natalia, Gornowicz, Agnieszka
Publicado no Drug Des Devel Ther (2017)

Pharmacokinetics of iron isomaltoside 1000 in patients with inflammatory bowel disease

Por Nordfjeld, Kim, Andreasen, Hans, Thomsen, Lars L
Publicado em 2012