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Effect of renal function on the pharmacokinetics of fimasartan: a single-dose, open-label, Phase I study
BACKGROUND: Fimasartan is a novel angiotensin II receptor blocker. Fimasartan is mainly eliminated via biliary excretion, and its urinary elimination is less than 3%. OBJECTIVE: Based on guidance from the United States Food and Drug Administration, a reduced pharmacokinetic (PK) study was conducted...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4199969/ https://ncbi.nlm.nih.gov/pubmed/25336916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S68784 |
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