An optimized probucol microencapsulated formulation integrating a secondary bile acid (deoxycholic acid) as a permeation enhancer

The authors have previously designed, developed, and characterized a novel microencapsulated formulation as a platform for the targeted delivery of therapeutics in an animal model of type 2 diabetes, using the drug probucol (PB). The aim of this study was to optimize PB microcapsules by incorporatin...

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Autors principals: Mooranian, Armin, Negrulj, Rebecca, Chen-Tan, Nigel, Watts, Gerald F, Arfuso, Frank, Al-Salami, Hani
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2014
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189710/
https://ncbi.nlm.nih.gov/pubmed/25302020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S68247
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