Resultados da pesquisa - brain tumor a treat

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3401

Genetically Engineered Multilineage-Differentiating Stress-Enduring Cells as Cellular Vehicles against Malignant Gliomas

Genetically Engineered Multilineage-Differentiating Stress-Enduring Cells as Cellular Vehicles against Malignant Gliomas

Por Yamasaki, Tomohiro, Wakao, Shohei, Kawaji, Hiroshi, Koizumi, Shinichiro, Sameshima, Tetsuro, Dezawa, Mari, Namba, Hiroki
Publicado no Mol Ther Oncolytics (2017)

“...Malignant glioma, the most common malignant brain tumor in adults, is difficult to treat due to its...”
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3402

IMMU-13. CRISPR/CAS9-MEDIATED SILENCING OF SHP-1 SIGNIFICANTLY ENHANCES THE ANTI-GLIOMA ACTIVITY OF IL-13Rα2 CAR T CELLS

IMMU-13. CRISPR/CAS9-MEDIATED SILENCING OF SHP-1 SIGNIFICANTLY ENHANCES THE ANTI-GLIOMA ACTIVITY OF IL-13Rα2 CAR T CELLS

Por Petersen, Christopher, Bell, Matthew, Houke, Haley, Yi, Zongzhen, Gottschalk, Stephen, Krenciute, Giedre
Publicado no Neuro Oncol (2019)

“... mice with IL-13Ra2.SHP-1-KO CAR T cells resulted in a significant delay in tumor growth and significant...”
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3403

MBCL-18. CHEK2 MUTATION IN HIGH-RISK MEDULLOBLASTOMA

MBCL-18. CHEK2 MUTATION IN HIGH-RISK MEDULLOBLASTOMA

Por Shah, Nidhi, Walter, Andrew
Publicado no Neuro Oncol (2018)

“..., could be due to activation of tumor predisposition genes. CHEK2 is cell cycle checkpoint kinase 2, a...”
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3404

PATH-56. CHEK2 MUTATION IN HIGH-RISK MEDULLOBLASTOMA

PATH-56. CHEK2 MUTATION IN HIGH-RISK MEDULLOBLASTOMA

Por Shah, Nidhi, Walter, Andrew
Publicado no Neuro Oncol (2018)

“..., could be due to activation of tumor predisposition genes. CHEK2 is cell cycle checkpoint kinase 2, a...”
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3405

AI-14 THE ANTI ANGIOGENIC AND INVASIVE EFFECTS OF AN INTEGRIN INHIBITOR AGAINST BEVACIZUMAB-INDUCED INVASIVE GLIOMA

AI-14 THE ANTI ANGIOGENIC AND INVASIVE EFFECTS OF AN INTEGRIN INHIBITOR AGAINST BEVACIZUMAB-INDUCED INVASIVE GLIOMA

Por Ishida, Joji, Onishi, Manabu, Kurozumi, Kazuhiko, Ichikawa, Tomotsugu, Fujii, Kentaro, Shimazu, Yosuke, Oka, Tetsuo, Otani, Yoshihiro, Shimizu, Toshihiko, Date, Isao
Publicado em 2014

“... intraperitoneally three times a week. At 18 days after tumor implantation, the brains were removed and observed...”
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3406

Increased serum interleukin-1β and interleukin-6 in elderly, chronic schizophrenic patients on stable antipsychotic medication

Increased serum interleukin-1β and interleukin-6 in elderly, chronic schizophrenic patients on stable antipsychotic medication

Por Schmitt, Andrea, Bertsch, Thomas, Tost, Heike, Bergmann, Andrea, Henning, Uwe, Klimke, Ansgar, Falkai, Peter
Publicado em 2005

“... such as infection, age, sex, smoking, and antipsychotic medication. Chronic schizophrenic patients with a long-term...”
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3407

PCLN-01. GENERATION, CHARACTERIZATION AND TREATMENT OF NOVEL MURINE MODELS FOR HUMAN PEDIATRIC GLIOMA

PCLN-01. GENERATION, CHARACTERIZATION AND TREATMENT OF NOVEL MURINE MODELS FOR HUMAN PEDIATRIC GLIOMA

Por Ismer, Britta, Moshe, Itai, Friedmann-Morvinski, Dinorah, Jones, David T W
Publicado no Neuro Oncol (2018)

“... new orthotopic brain tumor models, and that specific inhibitors against chosen oncogenes have a...”
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3408

IMMU-18. TARGETING THE PD1 AND TIGIT CHECKPOINT PATHWAYS FOR ADULT AND PEDIATRIC GLIOMAS

IMMU-18. TARGETING THE PD1 AND TIGIT CHECKPOINT PATHWAYS FOR ADULT AND PEDIATRIC GLIOMAS

Por Shoger, Karsen, McCarl, Lauren, Gilbert, Ryan, Villanueva, Clarence, Levy, Nicole, Amankulor, Nduka, Pollack, Ian, Kohanbash, Gary
Publicado no Neuro Oncol (2018)

“...High-grade gliomas (HGGs) are the most common and deadliest of malignant primary brain tumors...”
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3409

THER-16. INTERACTION OF IMMUNE SYSTEM WITH ONCOLYTIC MEASLES VIRUS THERAPY IN AN MV-SENSITIVE IMMUNOCOMPETENT MURINE MODEL OF MEDULLOBLASTOMA

THER-16. INTERACTION OF IMMUNE SYSTEM WITH ONCOLYTIC MEASLES VIRUS THERAPY IN AN MV-SENSITIVE IMMUNOCOMPETENT MURINE MODEL OF MEDULLOBLASTOMA

Por Lal, Sangeet, Mueller, Sabine, Gupta, Nalin, Raffel, Corey
Publicado no Neuro Oncol (2019)

“..., compared to normal brain (n=3). Tumors that responded to MV therapy, but recurred had a dramatic decrease...”
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3410

Charged particle therapy with mini-segmented beams

Charged particle therapy with mini-segmented beams

Por F. Avraham eDilmanian, John G Eley, Adam eRusek, Sunil eKrishnan
Publicado em 2015-12-01

“... target in a rabbit brain at a single exposure with 40 Gy physical absorbed dose. Contrast-enhanced...”
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3411

Computed modeling of alternating electric fields therapy for recurrent glioblastoma

Computed modeling of alternating electric fields therapy for recurrent glioblastoma

Por Lok, Edwin, Hua, Van, Wong, Eric T
Publicado no Cancer Med (2015)

“...Tumor treating fields (TTFields) are alternating electric fields frequency tuned to 200 kHz...”
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3412

MEDU-27. ENHANCING SELUMETINIB-MEDIATED KILLING OF SHH MEDULLOBLASTOMA

MEDU-27. ENHANCING SELUMETINIB-MEDIATED KILLING OF SHH MEDULLOBLASTOMA

Por Guppy, Brent, Liang, Lisa, Cheng, Stephen, Porter, Christopher, Werbowetski-Ogilvie, Tamra
Publicado no Neuro Oncol (2019)

“... chemotherapeutic strategies designed to better treat SHH MB are needed. A major contributing factor to cellular...”
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3413

The PD-1/B7-H1 Pathway Modulates the Natural Killer Cells versus Mouse Glioma Stem Cells

The PD-1/B7-H1 Pathway Modulates the Natural Killer Cells versus Mouse Glioma Stem Cells

Por Huang, Bo Yuan, Zhan, Yi Ping, Zong, Wen Jing, Yu, Chun Jiang, Li, Jun Fa, Qu, Yan Ming, Han, Song
Publicado no PLoS One (2015)

“...PURPOSE: Glioblastoma multiforme (GBM) is the most malignant primary type of brain tumor in adults...”
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3414

IMMU-12. TGFβ ACTIVATION BY RADIATION OPPOSES IMMUNE REJECTION OF INTRACRANIAL GL261

IMMU-12. TGFβ ACTIVATION BY RADIATION OPPOSES IMMUNE REJECTION OF INTRACRANIAL GL261

Por Barcellos-Hoff, Mary, Gonzalez-Junca, Alba, Vera, Denis Beckford, VanBrocklin, Henry, Franc, Benjamin, Parry, Renate
Publicado no Neuro Oncol (2018)

“...Enabling anti-tumor immunity in brain is a challenge due to its unique microenvironment...”
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3415

Subependymoma: clinical features and surgical outcomes

Subependymoma: clinical features and surgical outcomes

Por Jain, Amit, Amin, Anubhav G., Jain, Punya, Burger, Peter, Jallo, George I., Lim, Michael, Bettegowda, Chetan
Publicado no Neurol Res (2012)

“... were treated from 1990 through 2009, with a mean follow-up of 39 months. The clinical and radiological...”
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3416

Reactive Astrocytes Protect Melanoma Cells from Chemotherapy by Sequestering Intracellular Calcium through Gap Junction Communication Channels

Reactive Astrocytes Protect Melanoma Cells from Chemotherapy by Sequestering Intracellular Calcium through Gap Junction Communication Channels

Por Qingtang Lin, Krishnakumar Balasubramanian, Dominic Fan, Sun-Jin Kim, Lixia Guo, Hua Wang, Menashe Bar-Eli, Kenneth D. Aldape, Isaiah J. Fidler
Publicado em 2010-09-01

“...Brain metastases are highly resistant to chemotherapy. Metastatic tumor cells are known to exploit...”
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3417

Allergies and risk of head and neck cancer

Allergies and risk of head and neck cancer

Por Michaud, Dominique S., Langevin, Scott M., Eliot, Melissa, Nelson, Heather H., McClean, Michael D., Christensen, Brock C., Marsit, Carmen J., Kelsey, Karl T.
Publicado em 2012

“...BACKGROUND: Individuals with allergies have a heightened Th2 (T helper 2) immunity which may...”
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3418

Tryptophan PET Predicts Spatial and Temporal Patterns of Post-Treatment Glioblastoma Progression Detected by Contrast-Enhanced MRI

Tryptophan PET Predicts Spatial and Temporal Patterns of Post-Treatment Glioblastoma Progression Detected by Contrast-Enhanced MRI

Por Bosnyák, Edit, Kamson, David O., Robinette, Natasha L., Barger, Geoffrey R., Mittal, Sandeep, Juhász, Csaba
Publicado no J Neurooncol (2015)

“.... Increased amino acid uptake is often observed outside the contrast-enhancing brain tumor mass. In this study...”
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3419

Evaluation of methotrexate-conjugated gadolinium(III) for cancer diagnosis and treatment

Evaluation of methotrexate-conjugated gadolinium(III) for cancer diagnosis and treatment

Por Xu, Dan, Lu, Shu-Ting, Li, Yu-Shuang, Baidya, Aju, Mei, Hao, He, Yong, Wu, Bo
Publicado no Drug Des Devel Ther (2018)

“...BACKGROUND: Gliomas are one of the most common types of primary brain tumors. It is usually...”
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3420

Hypothalamic Gene Transfer of BDNF Inhibits Breast Cancer Progression and Metastasis in Middle Age Obese Mice

Hypothalamic Gene Transfer of BDNF Inhibits Breast Cancer Progression and Metastasis in Middle Age Obese Mice

Por Liu, Xianglan, McMurphy, Travis, Xiao, Run, Slater, Andrew, Huang, Wei, Cao, Lei
Publicado em 2014

“... phenotype in animal models of melanoma and colon cancer. Brain-derived neurotrophic factor (BDNF) is a key...”
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