Resultados da pesquisa - brain tumor ((cures treat) OR (cures trial))

Pesquisas alternativas:
brain tumor » brain tumors (Expandir a Pesquisa)
cures treat » aureus treat (Expandir a Pesquisa), res treat (Expandir a Pesquisa), cures threaten (Expandir a Pesquisa)
cures trial » cure trial (Expandir a Pesquisa), cues trial (Expandir a Pesquisa), caries trial (Expandir a Pesquisa)

21

Benefit from prolonged dose-intensive chemotherapy for infants with malignant brain tumors is restricted to patients with ependymoma: a report of the Pediatric Oncology Group randomized controlled trial 9233/34

Benefit from prolonged dose-intensive chemotherapy for infants with malignant brain tumors...

Por Strother, Douglas R., Lafay-Cousin, Lucie, Boyett, James M., Burger, Peter, Aronin, Patricia, Constine, Louis, Duffner, Patricia, Kocak, Mehmet, Kun, Larry E., Horowitz, Marc E., Gajjar, Amar
Publicado em 2014

“... with newly diagnosed malignant brain tumors. METHODS: Of 328 enrolled eligible patients, diagnoses were...”
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22

$Survival outcomes of patients with germ cell tumors treated with high-dose chemotherapy for refractory or relapsing disease$

Survival outcomes of patients with germ cell tumors treated with high-dose chemotherapy for refractory or relapsing disease

Por Zschäbitz, Stefanie, Distler, Florian A, Krieger, Benjamin, Wuchter, Patrick, Schäfer-Eckart, Kerstin, Jenzer, Maximilian, Hohenfellner, Markus, Dreger, Peter, Haag, Georg Martin, Jäger, Dirk, Pahernik, Sascha, Grüllich, Carsten
Publicado no Oncotarget (2018)

“...INTRODUCTION: Male patients with metastatic germ cell tumors can be cured in up to 96% of cases...”
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23

IMMU-17. HEMATOPOIETIC STEM CELL-DERIVED DENDRITIC CELLS REPROGRAM THE BRAIN TUMOR MICROENVIRONMENT

IMMU-17. HEMATOPOIETIC STEM CELL-DERIVED DENDRITIC CELLS REPROGRAM THE BRAIN TUMOR MICROENVIRONMENT

Por Wildes, Tyler, Flores, Catherine, DiVita, Bayli, Dyson, Kyle, Grippin, Adam, Mitchell, Duane
Publicado no Neuro Oncol (2018)

“... the differentiation of HSPCs into dendritic cells within the brain tumor microenvironment. METHODS: We evaluated HSPC...”
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24

A Pre-Clinical Assessment of the Pan-ERBB Inhibitor Dacomitinib in Pediatric and Adult Brain Tumors

A Pre-Clinical Assessment of the Pan-ERBB Inhibitor Dacomitinib in Pediatric and Adult Brain Tumors

Por Endersby, Raelene, Whitehouse, Jacqueline, Hii, Hilary, Greenall, Sameer A., Johns, Terrance G., Gottardo, Nicholas G.
Publicado no Neoplasia (2018)

“..., are aggressive brain tumors. The survival for patients with glioblastoma remains dismal. While the cure rate...”
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25

Comparing routes of delivery for nanoliposomal irinotecan shows superior anti-tumor activity of local administration in treating intracranial glioblastoma xenografts

Comparing routes of delivery for nanoliposomal irinotecan shows superior anti-tumor activity...

Por Chen, Pin-Yuan, Ozawa, Tomoko, Drummond, Daryl C., Kalra, Ashish, Fitzgerald, Jonathan B., Kirpotin, Dmitri B., Wei, Kuo-Chen, Butowski, Nicholas, Prados, Michael D., Berger, Mitchel S., Forsayeth, John R., Bankiewicz, Krystof, James, C. David
Publicado em 2013

“... for maximizing the anti-tumor effects of irinotecan and support clinical trial evaluation of this therapeutic...”
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26

Chimeric antigen receptor engineered T cells can eliminate brain tumors and initiate long-term protection against recurrence

Chimeric antigen receptor engineered T cells can eliminate brain tumors and initiate long-term protection against recurrence

Por Johnson, Laura A, Sanchez-Perez, Luis, Suryadevara, Carter M, Sampson, John H
Publicado no Oncoimmunology (2014)

“...CAR therapy has shown promise in treating cancer, but at the cost of unexpected toxicity against...”
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27

Comparing proton treatment plans of pediatric brain tumors in two pencil beam scanning nozzles with different spot sizes

Comparing proton treatment plans of pediatric brain tumors in two pencil beam scanning nozzles with different spot sizes

Por Kralik, John C., Xi, Liwen, Solberg, Timothy D., Simone, Charles B., Lin, Liyong
Publicado no J Appl Clin Med Phys (2015)

“... brain tumors treated using two distinct nozzles in pencil beam scanning (PBS) proton therapy...”
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28

CCR-08-0827 Version 2 Targeted inhibition of cyclic AMP phosphodiesterase-4 promotes brain tumor regression

CCR-08-0827 Version 2 Targeted inhibition of cyclic AMP phosphodiesterase-4 promotes brain tumor regression

Por Goldhoff, Patricia, Warrington, Nicole, Limbrick, David D., Hope, Andrew, Woerner, B. Mark, Jackson, Erin, Perry, Arie, Piwnica-Worms, David, Rubin, Joshua B.
Publicado em 2008

“... that PDE4 inhibition should be evaluated in clinical trials for malignant brain tumors. PURPOSE...”
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29

MBRS-53. ENHANCED EFFICACY OF NANO-FORMULATED VISMODEGIB SHOWS THE POTENTIAL FOR POLYOXAZOLINE MICELLES TO IMPROVE DRUG DELIVERY TO BRAIN TUMORS

MBRS-53. ENHANCED EFFICACY OF NANO-FORMULATED VISMODEGIB SHOWS THE POTENTIAL FOR POLYOXAZOLINE MICELLES TO IMPROVE DRUG DELIVERY TO BRAIN TUMORS

Por Hwang, Duhyeong, Zhao, Yuling, Liu, Hedi, Kabanov, Alexander, Gershon, Timothy, Sokolsky, Marina
Publicado no Neuro Oncol (2018)

“... agents for brain tumor therapy. The anti-tumor effect of vismodegib, optimized in POx-vismo...”
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30

Brain-derived neurotrophic factor involved epigenetic repression of UGT2B7 in colorectal carcinoma: A mechanism to alter morphine glucuronidation in tumor

Brain-derived neurotrophic factor involved epigenetic repression of UGT2B7 in colorectal carcinoma: A mechanism to alter morphine glucuronidation in tumor

Por Yang, Zi-Zhao, Li, Li, Xu, Ming-Cheng, Ju, Hai-Xing, Hao, Miao, Gu, Jing-Kai, Wang, Zai-Jie Jim, Jiang, Hui-Di, Yu, Lu-Shan, Zeng, Su
Publicado no Oncotarget (2017)

“... repressed in the tumor tissues of colorectal carcinoma (CRC) patients. Accordingly, morphine in CRC cells...”
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31

TMIC-15. OMX IS A TUMOR MICROENVIRONMENT MODIFIER THAT RESTORES ANTI-TUMOR IMMUNITY AND IMPROVES ANTI-TUMOR EFFICACY BY REDUCING TUMOR HYPOXIA IN INTRACRANIAL GLIOBLASTOMA MOUSE MODEL

TMIC-15. OMX IS A TUMOR MICROENVIRONMENT MODIFIER THAT RESTORES ANTI-TUMOR IMMUNITY AND IMPROVES...

Por Le Moan, Natacha, Davis, Tina, Leung, Philberta, Ng, Sarah, Winger, Jonathan, Cary, Stephen, Butowski, Nicholas, Krtolica, Ana
Publicado no Neuro Oncol (2018)

“... microenvironment and promote tumor cures. RESULTS: Following intravenous administration in brain tumor-bearing mice...”
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32

Combination Treatment with the GSK-3 Inhibitor 9-ING-41 and CCNU Cures Orthotopic Chemoresistant Glioblastoma in Patient-Derived Xenograft Models()()

Combination Treatment with the GSK-3 Inhibitor 9-ING-41 and CCNU Cures Orthotopic Chemoresistant Glioblastoma in Patient-Derived Xenograft Models()()

Por Ugolkov, Andrey, Qiang, Wenan, Bondarenko, Gennadiy, Procissi, Daniel, Gaisina, Irina, James, C. David, Chandler, James, Kozikowski, Alan, Gunosewoyo, Hendra, O'Halloran, Thomas, Raizer, Jeffrey, Mazar, Andrew P.
Publicado no Transl Oncol (2017)

“... (partial response to CCNU) PDX models, as indicated by a decrease in tumor bioluminescence in mouse brain...”
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33

The Profile of Tumor Antigens Which Can be Targeted by Immunotherapy Depends Upon the Tumor's Anatomical Site

Por Alonso-Camino, Vanesa, Rajani, Karishma, Kottke, Timothy, Rommelfanger-Konkol, Diana, Zaidi, Shane, Thompson, Jill, Pulido, Jose, Ilett, Elizabeth, Donnelly, Oliver, Selby, Peter, Pandha, Hardev, Melcher, Alan, Harrington, Kevin, Diaz, Rosa Maria, Vile, Richard
Publicado no Mol Ther (2014)

“... brain tumors. The optimal combination of antigens identified from the ASMEL which treated s.c. B16...”
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34

P11.08 Systematic drug repurposing for faster cures of pediatric cancer identifies that Digoxin prolongs survival in a PDOX model of group 4 medulloblastoma

P11.08 Systematic drug repurposing for faster cures of pediatric cancer identifies that Digoxin prolongs survival in a PDOX model of group 4 medulloblastoma

Por Huang, L., Injac, S. G., Zhao, H., Lin, Q., Kogiso, M., Man, C., Li, X., Lau, C., Wong, S. T. C.
Publicado no Neuro Oncol (2017)

“...Background: Medulloblastoma (MB) is the most common malignant brain tumor of childhood. While...”
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35

Tumors of the Central Nervous System in Children and Adolescents

Tumors of the Central Nervous System in Children and Adolescents

Por Frühwald, Michael C, Rutkowski, Stefan
Publicado em 2011

“... with medulloblastoma, the most common malignant CNS tumor in children, was about 20%. At present, in contrast, cure can...”
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36

ET-21 COMBINATION OF INTRAVENOUS AND INTRACEREBRAL INJECTION OF ONCOLYTIC PARVOVIRUS H-1 IN A PHASE I/IIA CLINICAL TRIAL OF PATIENTS WITH RECURRENT GLIOBLASTOMA MULTIFORME: PENETRATION OF H-1 VIRUS ACROSS THE BLOOD-BRAIN BARRIER

ET-21 COMBINATION OF INTRAVENOUS AND INTRACEREBRAL INJECTION OF ONCOLYTIC PARVOVIRUS H-1 IN A PHASE I/IIA CLINICAL TRIAL OF PATIENTS WITH RECURRENT GLIOBLASTOMA MULTIFORME: PENETRATION OF H-1 VIRUS...

Por Geletneky, Karsten, Angelova, Assia, Leuchs, Barbara, Bhat, Rauf, Just, Alexandra, Capper, David, Krebs, Ottheinz, Dahm, Michael, Huber, Bernard, Unterberg, Andreas, Hajda, Jacek, Rommelaere, Jean
Publicado em 2014

“... and whether also in humans virus particles can cross the blood-brain/tumor barrier. As the trial is currently...”
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37

Adenoviral-mediated Gene Transfer into the Canine Brain In Vivo

Adenoviral-mediated Gene Transfer into the Canine Brain In Vivo

Por Candolfi, Marianela, Kroeger, Kurt M., Pluhar, G. Elizabeth, Bergeron, Josee, Puntel, Mariana, Curtin, James F., McNiel, Elizabeth A., Freese, Andrew B., Ohlfest, John R., Moore, Peter, Lowenstein, Pedro R., Castro, Maria G.
Publicado em 2007

“...OBJECTIVE: Glioblastoma multiforme (GBM) is a devastating brain tumor for which there is no cure...”
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38

Thoughts about cancer stem cells in solid tumors

Thoughts about cancer stem cells in solid tumors

Por La Porta, Caterina AM
Publicado em 2012

“... represents a major challenge in treating and curing the most aggressive and metastatic cancers. On the other...”
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39

Efficacy assessment of pemetrexed treatment of an NSCLC case with brain metastasis

Efficacy assessment of pemetrexed treatment of an NSCLC case with brain metastasis

Por LIANG, JING, LIU, XIAOLIN, YIN, BEIBEI, LIU, HAIRONG, XIAO, JUNJUAN, LI, YAN
Publicado em 2012

“... is often used clinically to cure cancers, its efficacy in NSCLC patients with progressive brain metastases...”
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40

The Molecular Classification of Medulloblastoma: Driving the next generation clinical trials

The Molecular Classification of Medulloblastoma: Driving the next generation clinical trials

Por Leary, Sarah E. S., Olson, James M.
Publicado em 2012

“.... Medulloblastoma, the most common pediatric malignant brain tumor, is an example of a disease that has benefitted...”
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