Structure–activity exploration of a small-molecule Lipid II inhibitor

Por Fletcher, Steven, Yu, Wenbo, Huang, Jing, Kwasny, Steven M, Chauhan, Jay, Opperman, Timothy J, MacKerell, Alexander D, de Leeuw, Erik PH
Publicado no Drug Des Devel Ther (2015)

Timosaponin B-II ameliorates diabetic nephropathy via TXNIP, mTOR, and NF-κB signaling pathways in alloxan-induced mice

Por Yuan, Yong-Liang, Guo, Chang-Run, Cui, Ling-Ling, Ruan, Shi-Xia, Zhang, Chun-Feng, Ji, De, Yang, Zhong-Lin, Li, Fei
Publicado no Drug Des Devel Ther (2015)

Animal Models That Best Reproduce the Clinical Manifestations of Human Intoxication with Organophosphorus Compounds

Por Pereira, Edna F. R., Aracava, Yasco, DeTolla, Louis J., Beecham, E. Jeffrey, Basinger, G. William, Wakayama, Edgar J., Albuquerque, Edson X.
Publicado em 2014

MicroRNAs in Atrial Fibrillation: from Expression Signatures to Functional Implications

Por van den Berg, Nicoline W. E., Kawasaki, Makiri, Berger, Wouter R., Neefs, Jolien, Meulendijks, Eva, Tijsen, Anke J., de Groot, Joris R.
Publicado no Cardiovasc Drugs Ther (2017)

Effectiveness and Tolerability of Vildagliptin and the Single Pill Combination of Vildagliptin and Metformin in “Real-World” Management of Type 2 Diabetes Mellitus: The G-FORCE Stu...

Por Van Gaal, Luc, Hermans, Michel P., Daci, Evis, Denhaerynck, Kris, De Meester, Lut, MacDonald, Karen, Abraham, Ivo, Vancayzeele, Stefaan, Maris, Michael
Publicado no Diabetes Ther (2019)

Involvement of poly(ADP-ribose) polymerase-1 in development of spinal cord injury in Chinese individuals: a Chinese clinical study

Por Meng, Qing-Tao, Yang, Guang, Li, Ren-Bo, Nie, Jing-Xin, Zhou, Wei, Yu, Hong-De, Chen, Bo, Jiang, Li, Shang, Jing-Bo
Publicado no Drug Des Devel Ther (2017)

Resveratrol downregulates TNF-α-induced monocyte chemoattractant protein-1 in primary rat pulmonary artery endothelial cells by P38 mitogen-activated protein kinase signaling

Por Lin, Jian-Wei, Yang, Le-He, Ren, Zhuo-Chao, Mu, De-Guang, Li, Ya-Qing, Yan, Jian-Ping, Wang, Liang-Xing, Chen, Chun
Publicado no Drug Des Devel Ther (2019)

Exploratory study on the impact of switching to nilotinib in 18 patients with chronic myeloid leukemia in chronic phase with suboptimal response to imatinib

Por Ailawadhi, Sikander, Akard, Luke P., Miller, Carole B., Jillella, Anand, DeAngelo, Daniel J., Ericson, Solveig G., Lin, Felice, Warsi, Ghulam, Radich, Jerald
Publicado no Ther Adv Hematol (2016)

Clinical dosing regimen of selinexor maintains normal immune homeostasis and T cell effector function in mice: implications for combination with immunotherapy

Por Tyler, Paul M., Servos, Mariah M., de Vries, Romy C., Klebanov, Boris, Kashyap, Trinayan, Sacham, Sharon, Landesman, Yosef, Dougan, Michael, Dougan, Stephanie K.
Publicado no Mol Cancer Ther (2017)

Prospective study on nanoparticle albumin-bound paclitaxel in advanced breast cancer: clinical results and biological observations in taxane-pretreated patients

Por Fabi, Alessandra, Giannarelli, Diana, Malaguti, Paola, Ferretti, Gianluigi, Vari, Sabrina, Papaldo, Paola, Nisticò, Cecilia, Caterino, Mauro, De Vita, Roy, Mottolese, Marcella, Iacorossi, Laura, Cognetti, Francesco
Publicado no Drug Des Devel Ther (2015)

Efficacy of trabectedin in advanced soft tissue sarcoma: beyond lipo- and leiomyosarcoma

Por De Sanctis, Rita, Marrari, Andrea, Marchetti, Silvia, Mussi, Chiara, Balzarini, Luca, Lutman, Fabio Romano, Daolio, Primo, Bastoni, Stefano, Bertuzzi, Alexia Francesca, Quagliuolo, Vittorio, Santoro, Armando
Publicado no Drug Des Devel Ther (2015)

Increasing expression of substance P and calcitonin gene-related peptide in synovial tissue and fluid contribute to the progress of arthritis in developmental dysplasia of the hip

Por Wang, Hui, Zhang, Xiang, He, Ji-Ye, Zheng, Xin-Feng, Li, De, Li, Zheng, Zhu, Jun-Feng, Shen, Chao, Cai, Gui-Quan, Chen, Xiao-Dong
Publicado no Arthritis Res Ther (2015)

Nanostructured lipid carriers for incorporation of copper(II) complexes to be used against Mycobacterium tuberculosis

Por Sato, Mariana R, Oshiro Junior, João A, Machado, Rachel TA, de Souza, Paula C, Campos, Débora L, Pavan, Fernando R, da Silva, Patricia B, Chorilli, Marlus
Publicado no Drug Des Devel Ther (2017)

Statins and aspirin in the prevention of cardiovascular disease among HIV-positive patients between controversies and unmet needs: review of the literature and suggestions for a fr...

Por Maggi, P., De Socio, G. V., Cicalini, S., D’Abbraccio, M., Dettorre, G., Di Biagio, A., Martinelli, C., Nunnari, G., Rusconi, S., Sighinolfi, L., Spagnuolo, V., Squillace, N.
Publicado no AIDS Res Ther (2019)

Stearoyl gemcitabine nanoparticles overcome obesity-induced cancer cell resistance to gemcitabine in a mouse postmenopausal breast cancer model

Por De Angel, Rebecca E., Blando, Jorge M., Hogan, Matthew G., Sandoval, Michael A., Lansakara-P, Dharmika S.P., Dunlap, Sarah M., Hursting, Stephen D., Cui, Zhengrong
Publicado em 2013

Deferasirox drives ROS-mediated differentiation and induces interferon-stimulated gene expression in human healthy haematopoietic stem/progenitor cells and in leukemia cells

Por Tataranni, Tiziana, Mazzoccoli, Carmela, Agriesti, Francesca, De Luca, Luciana, Laurenzana, Ilaria, Simeon, Vittorio, Ruggieri, Vitalba, Pacelli, Consiglia, Della Sala, Gerardo, Musto, Pellegrino, Capitanio, Nazzareno, Piccoli, Claudia
Publicado no Stem Cell Res Ther (2019)

The combination astemizole–gefitinib as a potential therapy for human lung cancer

Por Chávez-López, María de Guadalupe, Zúñiga-García, Violeta, Hernández-Gallegos, Elisabeth, Vera, Eunice, Chasiquiza-Anchatuña, Carmen Alexandra, Viteri-Yánez, Marco, Sanchez-Ramos, Janet, Garrido, Efraín, Camacho, Javier
Publicado no Onco Targets Ther (2017)

Therapeutic efficacy in a hemophilia B model using a biosynthetic mRNA liver depot system

Por DeRosa, F, Guild, B, Karve, S, Smith, L, Love, K, Dorkin, J R, Kauffman, K J, Zhang, J, Yahalom, B, Anderson, D G, Heartlein, M W
Publicado no Gene Ther (2016)

Fondaparinux vs warfarin for the treatment of unsuspected pulmonary embolism in cancer patients

Por Amato, Bruno, Compagna, Rita, Rocca, Aldo, Bianco, Tommaso, Milone, Marco, Sivero, Luigi, Vigliotti, Gabriele, Amato, Maurizio, Danzi, Michele, Aprea, Giovanni, Gallelli, Luca, de Franciscis, Stefano, Serra, Raffaele
Publicado no Drug Des Devel Ther (2016)

The need for comparative data in spondyloarthritis

Por Choy, Ernest, Baraliakos, Xenofon, Behrens, Frank, D’Angelo, Salvatore, de Vlam, Kurt, Kirkham, Bruce W., Østergaard, Mikkel, Schett, Georg A., Rissler, Michael, Chaouche-Teyara, Kamel, Perella, Chiara
Publicado no Arthritis Res Ther (2019)