Resultados da pesquisa - (( j l comer can newts ) OR ((( 3 natl (camp OR cap) c new ) OR ( a rain company carlos noe ))))

Pesquisas alternativas:
comer » comes (Expandir a Pesquisa), comet (Expandir a Pesquisa), homer (Expandir a Pesquisa)
camp » cam (Expandir a Pesquisa), comp (Expandir a Pesquisa), came (Expandir a Pesquisa)
rain » ran (Expandir a Pesquisa), raiz (Expandir a Pesquisa), rai (Expandir a Pesquisa)
noe » none (Expandir a Pesquisa), node (Expandir a Pesquisa), note (Expandir a Pesquisa)

1

Small-molecule synergist of the Wnt/β-catenin signaling pathway

Small-molecule synergist of the Wnt/β-catenin signaling pathway

Por Zhang, Qisheng, Major, Michael B., Takanashi, Shinichi, Camp, Nathan D., Nishiya, Naoyuki, Peters, Eric C., Ginsberg, Mark H., Jian, Xiaoying, Randazzo, Paul A., Schultz, Peter G., Moon, Randall T., Ding, Sheng
Publicado em 2007

“... of Wnt/β-catenin signaling and discovered a purine derivative, QS11, that synergizes with Wnt-3a ligand...”
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2

Three-dimensional structure of a protein from scorpion venom: a new structural class of neurotoxins.

Three-dimensional structure of a protein from scorpion venom: a new structural class of neurotoxins.

Por Fontecilla-Camps, J C, Almassy, R J, Suddath, F L, Watt, D D, Bugg, C E
Publicado em 1980

“...The three-dimensional crystal structure of variant-3 toxin from the scorpion Centruroides...”
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3

Structural basis for m7G recognition and 2′-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I

Structural basis for m7G recognition and 2′-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I

Por Devarkar, Swapnil C., Wang, Chen, Miller, Matthew T., Ramanathan, Anand, Jiang, Fuguo, Khan, Abdul G., Patel, Smita S., Marcotrigiano, Joseph
Publicado no Proc Natl Acad Sci U S A (2016)

“... show that RIG-I can accommodate the m7G cap in a cavity created through conformational changes...”
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4

Cloning and characterization of a cAMP-specific cyclic nucleotide phosphodiesterase

Cloning and characterization of a cAMP-specific cyclic nucleotide phosphodiesterase

Por Soderling, S. H., Bayuga, S. J., Beavo, J. A.
Publicado em 1998

“... of a novel cAMP-specific PDE from mouse testis. This unique phosphodiesterase contains a catalytic...”
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5

Identification of an essential serine residue in glucagon: implication for an active site triad.

Identification of an essential serine residue in glucagon: implication for an active site triad.

Por Unson, C G, Merrifield, R B
Publicado em 1994

“... inhibitor of serine proteases, which at a concentration of 5 mM completely suppressed cAMP formation...”
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6

Calcitonin gene-related peptide stimulates proliferation of human endothelial cells.

Calcitonin gene-related peptide stimulates proliferation of human endothelial cells.

Por Haegerstrand, A, Dalsgaard, C J, Jonzon, B, Larsson, O, Nilsson, J
Publicado em 1990

“... of specific CGRP receptors. The effect of CGRP on formation of adenosine 3',5'-cyclic monophosphate (cAMP...”
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7

Cell-type-specific responses of RT4 neural cell lines to dibutyryl-cAMP: branch determination versus maturation.

Cell-type-specific responses of RT4 neural cell lines to dibutyryl-cAMP: branch determination versus maturation.

Por Droms, K, Sueoka, N
Publicado em 1987

“... of dibutyryl-cAMP. This indicates that conversion of RT4-AC to the derivative cell types is also a branch point...”
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8

Crystal structure of the SarR protein from Staphylococcus
aureus

Crystal structure of the SarR protein from Staphylococcus aureus

Por Liu, Yingfang, Manna, Adhar, Li, Ronggui, Martin, Wesley E., Murphy, Robert C., Cheung, Ambrose L., Zhang, Gongyi
Publicado em 2001

“... regulatory loci (e.g., sarA and agr). The sar (Staphylococcus accessory regulator) locus is composed of three...”
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9

Cyclic AMP induces transforming growth factor beta 2 gene expression and growth arrest in the human androgen-independent prostate carcinoma cell line PC-3.

Cyclic AMP induces transforming growth factor beta 2 gene expression and growth arrest in the human androgen-independent prostate carcinoma cell line PC-3.

Por Bang, Y J, Kim, S J, Danielpour, D, O'Reilly, M A, Kim, K Y, Myers, C E, Trepel, J B
Publicado em 1992

“... cAMP markedly inhibits the growth of the hormone-refractory cell line PC-3. To examine the mechanism...”
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10

Scientific basis for safely shutting in the Macondo Well after the April 20, 2010 Deepwater Horizon blowout

Scientific basis for safely shutting in the Macondo Well after the April 20, 2010 Deepwater Horizon blowout

Por Hickman, Stephen H., Hsieh, Paul A., Mooney, Walter D., Enomoto, Catherine B., Nelson, Philip H., Mayer, Larry A., Weber, Thomas C., Moran, Kathryn, Flemings, Peter B., McNutt, Marcia K.
Publicado em 2012

“... around the Macondo Well. After the well was successfully capped and shut in on July 15, 2010, a variety...”
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11

New protein kinase and protein phosphatase families mediate signal transduction in bacterial catabolite repression

New protein kinase and protein phosphatase families mediate signal transduction in bacterial catabolite repression

Por Galinier, Anne, Kravanja, Melanie, Engelmann, Roswitha, Hengstenberg, Wolfgang, Kilhoffer, Marie-Claude, Deutscher, Josef, Haiech, Jacques
Publicado em 1998

“... bacteria, cAMP was considered to be the second messenger in CCR by playing a role reminiscent of its...”
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12

IGF-1R and mTOR Blockade: Novel Resistance Mechanisms and Synergistic Drug Combinations for Ewing Sarcoma

IGF-1R and mTOR Blockade: Novel Resistance Mechanisms and Synergistic Drug Combinations for Ewing Sarcoma

Por Lamhamedi-Cherradi, Salah-Eddine, Menegaz, Brian A., Ramamoorthy, Vandhana, Vishwamitra, Deeksha, Wang, Ying, Maywald, Rebecca L., Buford, Adriana S., Fokt, Izabela, Skora, Stanislaw, Wang, Jing, Naing, Aung, Lazar, Alexander J., Rohren, Eric M., Daw, Najat C., Subbiah, Vivek, Benjamin, Robert S., Ratan, Ravin, Priebe, Waldemar, Mikos, Antonios G., Amin, Hesham M., Ludwig, Joseph A.
Publicado no J Natl Cancer Inst (2016)

“..., which was also induced by OSI-906. pEIF4E(Ser209), a key regulator of Cap-dependent translation...”
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13

The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding

The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding

Por Martinez, Sergio E., Wu, Albert Y., Glavas, Natalie A., Tang, Xiao-Bo, Turley, Stewart, Hol, Wim G. J., Beavo, Joseph A.
Publicado em 2002

“...Cyclic nucleotide phosphodiesterases (PDEs) regulate all pathways that use cGMP or cAMP as a second...”
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14

Vasoactive intestinal peptide inhibits human small-cell lung cancer proliferation in vitro and in vivo

Vasoactive intestinal peptide inhibits human small-cell lung cancer proliferation in vitro and in vivo

Por Maruno, Kaname, Absood, Afaf, Said, Sami I.
Publicado em 1998

“... cases, the inhibition was mediated apparently by a cAMP-dependent mechanism, because the inhibition...”
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15

Mechanism for the autogenous control of the crp operon: transcriptional inhibition by a divergent RNA transcript.

Mechanism for the autogenous control of the crp operon: transcriptional inhibition by a divergent RNA transcript.

Por Okamoto, K, Freundlich, M
Publicado em 1986

“... receptor protein (cAMP-CRP). We find a second promoter in this region that is strongly activated in vitro...”
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16

Isolation and characterization of a dual-substrate phosphodiesterase gene family: PDE10A

Isolation and characterization of a dual-substrate phosphodiesterase gene family: PDE10A

Por Soderling, Scott H., Bayuga, Sharon J., Beavo, Joseph A.
Publicado em 1999

“... and, therefore, represents a new PDE gene family, designated PDE10A. The cDNA for PDE10A is 3,370 nt in length...”
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17

An isoform of the rod photoreceptor cyclic nucleotide-gated channel β subunit expressed in olfactory neurons

An isoform of the rod photoreceptor cyclic nucleotide-gated channel β subunit expressed in olfactory neurons

Por Sautter, Andrea, Zong, Xiangang, Hofmann, Franz, Biel, Martin
Publicado em 1998

“... coexpression of CNG2, CNG4.3, and CNG5, a conductance with a cAMP sensitivity greater than that of either...”
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18

Attenuation of insulin secretion by insulin-like growth factor 1 is mediated through activation of phosphodiesterase 3B

Attenuation of insulin secretion by insulin-like growth factor 1 is mediated through activation of phosphodiesterase 3B

Por Zhao, Allan Z., Zhao, Hong, Teague, Jeanette, Fujimoto, Wilfred, Beavo, Joseph A.
Publicado em 1997

“.... Insulin secretion stimulated by cAMP analogs that activate protein kinase A and also are substrates...”
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19

Activation of muscarinic acetylcholine receptors via their allosteric binding sites.

Activation of muscarinic acetylcholine receptors via their allosteric binding sites.

Por Jakubík, J, Bacáková, L, Lisá, V, el-Fakahany, E E, Tucek, S
Publicado em 1996

“... of an agonist) alter the synthesis of cAMP in Chinese hamster ovary (CHO) cells expressing the M2 or the M4...”
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20

Crystal structure of the tandem GAF domains from a cyanobacterial adenylyl cyclase: Modes of ligand binding and dimerization

Crystal structure of the tandem GAF domains from a cyanobacterial adenylyl cyclase: Modes of ligand binding and dimerization

Por Martinez, Sergio E., Bruder, Sandra, Schultz, Anita, Zheng, Ning, Schultz, Joachim E., Beavo, Joseph A., Linder, Jürgen U.
Publicado em 2005

“... domains of cyaB2 with bound cAMP and compare it to the previously reported structure of the PDE2A GAF-A/B...”
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