Resultados da pesquisa - (( j e ((comp can) OR (camp can)) now ) OR ((( j nay clamp a new ) OR ( j le congo case ngoc ))))

1

Associative conditioning analog selectively increases cAMP levels of tail sensory neurons in Aplysia.

Por Ocorr, K A, Walters, E T, Byrne, J H
Publicado em 1985

“... that this facilitation can be selectively amplified by the application of a classical conditioning procedure...”
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2

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Activation of muscarinic acetylcholine receptors via their allosteric binding sites.

Por Jakubík, J, Bacáková, L, Lisá, V, el-Fakahany, E E, Tucek, S
Publicado em 1996

“... their allosteric, binding sites. This represents a new mechanism of receptor activation....”
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3

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New DAG and cAMP Sensors Optimized for Live-Cell Assays in Automated Laboratories

Por Tewson, Paul H., Martinka, Scott, Shaner, Nathan C., Hughes, Thomas E., Quinn, Anne Marie
Publicado no J Biomol Screen (2015)

“..., but their use in automated laboratories is limited. We have now created two live-cell assays, one for diacyl...”
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4

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Selective inhibition of HDAC8 decreases neuroblastoma growth in vitro and in vivo and enhances retinoic acid-mediated differentiation

Por Rettig, I, Koeneke, E, Trippel, F, Mueller, W C, Burhenne, J, Kopp-Schneider, A, Fabian, J, Schober, A, Fernekorn, U, von Deimling, A, Deubzer, H E, Milde, T, Witt, O, Oehme, I
Publicado no Cell Death Dis (2015)

“... are currently under investigation for the treatment of a broad spectrum of cancer diseases. However, one...”
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5

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Relaxin Family Peptide Receptors – former orphans reunite with their parent ligands to activate multiple signalling pathways

Por Halls, M L, van der Westhuizen, E T, Bathgate, R A D, Summers, R J
Publicado em 2007

“...The relaxin family peptides, although structurally closely related to insulin, act on a group...”
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6

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Do Frogs Get Their Kicks on Route 66? Continental U.S. Transect Reveals Spatial and Temporal Patterns of Batrachochytrium dendrobatidis Infection

Por Lannoo, Michael J., Petersen, Christopher, Lovich, Robert E., Nanjappa, Priya, Phillips, Christopher, Mitchell, Joseph C., Macallister, Irene
Publicado em 2011

“..., spreading as a wave and wiping out individuals, populations, and species in its path; and Bd is endemic...”
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7

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Phase-Variable Expression of lptA Modulates the Resistance of Neisseria gonorrhoeae to Cationic Antimicrobial Peptides

Por Kandler, Justin L., Joseph, Sandeep J., Balthazar, Jacqueline T., Dhulipala, Vijaya, Read, Timothy D., Jerse, Ann E., Shafer, William M.
Publicado em 2014

“... experimental infection. We now report that the lptA gene, which encodes the PEA transferase responsible...”
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8

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Molecular Epidemiology of Aspergillus fumigatus Isolates Harboring the TR(34)/L98H Azole Resistance Mechanism

Por Camps, Simone M. T., Rijs, Antonius J. M. M., Klaassen, Corné H. W., Meis, Jacques F., O'Gorman, Céline M., Dyer, Paul S., Melchers, Willem J. G., Verweij, Paul E.
Publicado em 2012

“... and involves the TR(34)/L98H mutations in cyp51A. This resistance mechanism is now also increasingly being...”
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9

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High Prevalence of Human T-Lymphotropic Virus Infection in Indigenous Women from the Peruvian Amazon

Por Blas, Magaly M., Alva, Isaac E., García, Patricia J., Cárcamo, Cesar, Montano, Silvia M., Mori, Nicanor, Muñante, Ricardo, Zunt, Joseph R.
Publicado em 2013

“... of the Shipibo-Konibo ethnic group. As both HTLV and HPV can be transmitted sexually, we now report a population...”
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10

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Regulation of nephron water and electrolyte transport by adenylyl cyclases

Por Rieg, Timo, Kohan, Donald E.
Publicado em 2014

“...Adenylyl cyclases (AC) catalyze formation of cAMP, a critical component of G protein-coupled...”
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11

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Cryopreservation and in vitro culture of primary cell types from lung tissue of a stranded pygmy sperm whale (Kogia breviceps)

Por Mancia, Annalaura, Spyropoulos, Demetri D., McFee, Wayne E., Newton, Danforth A., Baatz, John E.
Publicado em 2011

“... with immortalized murine or human cell lines. To develop a new more powerful model system, we have pursued methods...”
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12

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Guanfacine for the Treatment of Cognitive Disorders: A Century of Discoveries at Yale

Por Arnsten, Amy F.T., Jin, Lu E.
Publicado em 2012

“... has found that the noradrenergic α2A agonist guanfacine can improve PFC function by strengthening PFC...”
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13

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Structural Basis for the Design of Selective Phosphodiesterase 4B Inhibitors

Por Fox, David, Burgin, Alex B., Gurney, Mark E.
Publicado em 2013

“... PDE4 subtypes (PDE4A-D). We show that highly selective PDE4B inhibitors can be designed by exploiting...”
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A retinoic acid-responsive element is present in the 5' flanking region of the laminin B1 gene.

Por Vasios, G W, Gold, J D, Petkovich, M, Chambon, P, Gudas, L J
Publicado em 1989

“... laminin B1 promoter/CAT expression vectors (e.g., p1.6LAMCAT) in RA-treated F9 cells, as measured in a...”
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15

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Regulation of endometrial cancer cell growth by luteinizing hormone (LH) and follicle stimulating hormone (FSH)

Por Davies, S, Bax, C M R, Chatzaki, E, Chard, T, Iles, R K
Publicado em 2000

“... cAMP production in either of our endometrial cancer cell lines. Thus, although a growth response to LH...”
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16

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Shiga toxin (Stx)1B and Stx2B induce von Willebrand factor secretion from human umbilical vein endothelial cells through different signaling pathways

Por Liu, Fang, Huang, Jing, Sadler, J. Evan
Publicado em 2011

“... endothelial cells (HUVECs), and Stx2B can cause thrombotic microangiopathy in Adamts13(−/−) mice. We have now...”
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17

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Xpr1 Is an Atypical G-Protein-Coupled Receptor That Mediates Xenotropic and Polytropic Murine Retrovirus Neurotoxicity

Por Vaughan, Andrew E., Mendoza, Ramon, Aranda, Ramona, Battini, Jean-Luc, Miller, A. Dusty
Publicado em 2012

“... retrovirus binding can disrupt the cAMP-mediated signaling function of Xpr1, leading to the apoptosis...”
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18

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ΔRaf-1:ER* Bypasses the Cyclic AMP Block of Extracellular Signal-Regulated Kinase 1 and 2 Activation but Not CDK2 Activation or Cell Cycle Reentry

Por Balmanno, Kathryn, Millar, Tracy, McMahon, Martin, Cook, Simon J.
Publicado em 2003

“...Elevation of cellular cyclic AMP (cAMP) levels inhibits cell cycle reentry in a variety of cell...”
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19

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Development of a Unique Small Molecule Modulator of CXCR4

Por Liang, Zhongxing, Zhan, Weiqiang, Zhu, Aizhi, Yoon, Younghyoun, Lin, Songbai, Sasaki, Maiko, Klapproth, Jan-Michael A., Yang, Hua, Grossniklaus, Hans E., Xu, Jianguo, Rojas, Mauricio, Voll, Ronald J., Goodman, Mark M., Arrendale, Richard F., Liu, Jin, Yun, C. Chris, Snyder, James P., Liotta, Dennis C., Shim, Hyunsuk
Publicado em 2012

“... the most devastating attribute and plays a major role in the morbidity and mortality of cancer...”
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20

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Cell-free transcription directed by the 422 adipose P2 gene promoter: activation by the CCAAT/enhancer binding protein.

Por Cheneval, D, Christy, R J, Geiman, D, Cornelius, P, Lane, M D
Publicado em 1991

“...Previous investigations have shown that CCAAT/enhancer binding protein (C/EBP) can function as a...”
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