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Selective inhibition of HDAC8 decreases neuroblastoma growth in vitro and in vivo and enhances retinoic acid-mediated differentiation
For differentiation-defective malignancies, compounds that modulate transcription, such as retinoic acid and histone deacetylase (HDAC) inhibitors, are of particular interest. HDAC inhibitors are currently under investigation for the treatment of a broad spectrum of cancer diseases. However, one cli...
में बचाया:
में प्रकाशित: | Cell Death Dis |
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मुख्य लेखकों: | , , , , , , , , , , , , , |
स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
Nature Publishing Group
2015
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4669789/ https://ncbi.nlm.nih.gov/pubmed/25695609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.24 |
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