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Relaxin Family Peptide Receptors – former orphans reunite with their parent ligands to activate multiple signalling pathways

The relaxin family peptides, although structurally closely related to insulin, act on a group of four G protein-coupled receptors now known as Relaxin Family Peptide (RXFP) Receptors. The leucine-rich repeat containing RXFP1 and RXFP2 and the small peptide-like RXFP3 and RXFP4 are the physiological...

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Detalhes bibliográficos
Main Authors: Halls, M L, van der Westhuizen, E T, Bathgate, R A D, Summers, R J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013861/
https://ncbi.nlm.nih.gov/pubmed/17293890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707140
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