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1
Por Cole, Graham B., Keum, Gyochang, Liu, Jie, Small, Gary W., Satyamurthy, Nagichettiar, Kepe, Vladimir, Barrio, Jorge R.
Publicado em 2010
“...) to produce molecular imaging probes for this enzyme. SULT1E1 is a key enzyme in estrogen homeostasis, playing...”Publicado em 2010
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2
Por Hall, Jason C., Marlow, Laura A., Mathias, Adam C., Dawson, Louis K., Durham, William F., Meshaw, Kenneth A., Mullin, Robert J., Synnott, Aidan J., Small, Daniel L., Krishna, Murli, von Hoff, Daniel, Schüler, Julia, Hart, Steven N., Couch, Fergus J., Colon-Otero, Gerardo, Copland, John A.
Publicado no J Transl Med (2016)
“...BACKGROUND: Pancreatic acinar cell carcinoma (PACC) is a rare malignancy, accounting for <1...”Publicado no J Transl Med (2016)
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3
“...Lung cancer is a heterogeneous group of disorders that is now being subdivided into molecular...”
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4
Por Lisk, Godfrey, Pain, Margaret, Sellers, Morgan, Gurnev, Philip A., Pillai, Ajay D., Bezrukov, Sergey M., Desai, Sanjay A.
Publicado em 2010
“.... These changes may be mediated by an unusual small conductance ion channel known as the plasmodial surface anion...”Publicado em 2010
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5
Por Walters, Robert W., Shumilin, Igor A., Yoon, Je-Hyun, Minor, Wladek, Parker, Roy
Publicado em 2014
“...The control of mRNA translation and degradation is mediated in part by a set of proteins that can...”Publicado em 2014
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6
Por Kirpotina, Liliya N., Khlebnikov, Andrei I., Schepetkin, Igor A., Ye, Richard D., Rabiet, Marie-Josèphe, Jutila, Mark A., Quinn, Mark T.
Publicado em 2010
“...N-formyl peptide receptor (FPR1) and N-formyl peptide receptor-like 1 (FPRL1, now known as FPR2...”Publicado em 2010
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7
Por Kolla, Likhitha, Heo, David S., Rosenberg, Daniel P., Barlow, Sara A., Maximova, Anna A., Cassio, Emily E., Buchser, William J.
Publicado no Sci Data (2018)
“... in vitro. Here, we describe a high content screen from which we identified small chemical compounds...”Publicado no Sci Data (2018)
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8
Por Zhang, Zhe, Martiny, Virginie, Lagorce, David, Ikeguchi, Yoshihiko, Alexov, Emil, Miteva, Maria A.
Publicado em 2014
“...Snyder-Robinson Syndrome (SRS) is a rare mental retardation disorder which is caused...”Publicado em 2014
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9
Por Chan, Leo L., Lidstone, Erich A., Finch, Kristin E., Heeres, James T., Hergenrother, Paul J., Cunningham, Brian T.
Publicado em 2009
“... in pharmaceutical discovery programs. It is now recognized that a substantial fraction of small molecules exhibit...”Publicado em 2009
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10
Por Reilley, Kate J., Giulianotti, Marc, Dooley, Colette T., Nefzi, Adel, McLaughlin, Jay P., Houghten, Richard A.
Publicado em 2010
“... libraries can be screened directly in vivo to identify individual compounds, potentially accelerating...”Publicado em 2010
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11
Por Tardif, Steve, Madamidola, Oladipo A., Brown, Sean G., Frame, Lorna, Lefièvre, Linda, Wyatt, Paul G., Barratt, Christopher L.R., Martins Da Silva, Sarah J.
Publicado no Hum Reprod (2014)
“... of treatment. Effects of compounds on sperm motility were assessed by computer-assisted sperm analysis. A...”Publicado no Hum Reprod (2014)
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12
Por Hamlin, Gordon A.
Publicado em 2000
“... of large numbers of small-scale reactions is both time-consuming and tedious, and is a rate limiting step...”Publicado em 2000
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13
Por Phillips-Howard, P A
Publicado em 1989
“... drugs, malaria preventive guidelines switched from chloroquine to the newer compound antimalarial drugs...”Publicado em 1989
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14
Por Bai, Ru, Zhang, Xing-Jie, Li, Yan-Li, Liu, Jing-Ping, Zhang, Hong-Bin, Xiao, Wei-Lie, Pu, Jian-Xin, Sun, Han-Dong, Zheng, Yong-Tang, Liu, Li-Xin
Publicado no BMC Microbiol (2015)
“... by various mechanisms. Until now, only a few small-molecule compounds that inhibit nuclear entry of viral DNA...”Publicado no BMC Microbiol (2015)
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15
“... to sample small volumes with negligible waste reduces reagent costs, compound usage and consumption of cells...”
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16
Por Aggarwal, M, Saxena, R, Sinclair, E, Fu, Y, Jacobs, A, Dyba, M, Wang, X, Cruz, I, Berry, D, Kallakury, B, Mueller, S C, Agostino, S D, Blandino, G, Avantaggiati, M L, Chung, F-L
Publicado no Cell Death Differ (2016)
“... that small molecules can rescue activity from mutant p53 by restoring WT tumor-suppressive functions...”Publicado no Cell Death Differ (2016)
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17
“... with the identification and characterization of a translational read-through compound, PTC124. PTC124 demonstrates a new...”
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18
“... provides a comprehensive look at possible targets for small molecule intervention as well as some new...”
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19
“... problem, which can be overcome by finding new inhibitors. Many new compounds active against T315I mutants...”
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20
“... channels. This has taken a great leap forward with the identification of the potentiator VX-770, now...”
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