Resultados da pesquisa - (( drugs diet devel ther ) OR ( drug doses devoid ther ))*

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Low-dose metronomic oral dosing of a prodrug of Gemcitabine (LY2334737) causes anti-tumor effects in the absence of inhibition of systemic vasculogenesis

Por Francia, Giulio, Shaked, Yuval, Hashimoto, Kae, Sun, John, Yin, Melissa, Cesta, Carolyn, Xu, Ping, Man, Shan, Hackl, Christina, Stewart, Julie, Uhlik, Mark, Dantzig, Anne H., Foster, Stuart, Kerbel, Robert S.
Publicado em 2011

“... drugs at relatively low minimally toxic doses with no prolonged break periods; it is now showing...”
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Edible bird’s nest attenuates procoagulation effects of high-fat diet in rats

Por Yida, Zhang, Imam, Mustapha Umar, Ismail, Maznah, Ismail, Norsharina, Hou, Zhiping
Publicado no Drug Des Devel Ther (2015)

“... diet- (HFD-) induced coagulation in rats were evaluated. Rats were fed for 12 weeks with HFD alone...”
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Pustular drug eruption due to Panax notoginseng saponins

Por Yin, ZhiQiang, Ma, LiWen, Xu, JiaLi, Xia, JiPing, Luo, Dan
Publicado em 2014

“... female) with drug eruption induced by PNS injection. All developed a sudden skin rash with pruritus from...”
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Effects of low-carbohydrate diet therapy in overweight subjects with autoimmune thyroiditis: possible synergism with ChREBP

Por Esposito, Teresa, Lobaccaro, Jean Marc, Esposito, Maria Grazia, Monda, Vincenzo, Messina, Antonietta, Paolisso, Giuseppe, Varriale, Bruno, Monda, Marcellino, Messina, Giovanni
Publicado no Drug Des Devel Ther (2016)

“... with high amounts of Abs. In a diet devoid of carbohydrates (bread, pasta, fruit, and rice), free from...”
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Development of PPAR-agonist GW0742 as antidiabetic drug: study in animals

Por Niu, Ho-Shan, Ku, Po-Ming, Niu, Chiang-Shan, Cheng, Juei-Tang, Lee, Kung-Shing
Publicado no Drug Des Devel Ther (2015)

“... HOMA-IR in diabetic rats fed a fructose-rich diet. This action was blocked by GSK0660 at the dose...”
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Effect of 7-Difluoromethyl-5, 4′-dimethoxygenistein on aorta atherosclerosis in hyperlipidemia ApoE(−/−) mice induced by a cholesterol-rich diet

Por Zhang, Yong, Li, Lesai, You, Jiliang, Cao, Jianguo, Fu, Xiaohua
Publicado em 2013

“... prophylactic treatment with different drugs at the beginning of the 16 week high-fat diet: 5 mg/gk genistein...”
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Acetazolamide serves as selective delivery vehicle for dipeptide-linked drugs to renal cell carcinoma

Por Cazzamalli, Samuele, Dal Corso, Alberto, Neri, Dario
Publicado no Mol Cancer Ther (2016)

“... carcinomas, while drug derivatives devoid of the acetazolamide moiety did not exhibit any detectable...”
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Drug development strategies for the treatment of obesity: how to ensure efficacy, safety, and sustainable weight loss

Por Barja-Fernandez, S, Leis, R, Casanueva, FF, Seoane, LM
Publicado no Drug Des Devel Ther (2014)

“.... Considering the limited efficacy of diet and exercise in the current obese population and the use of bariatric...”
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Naltrexone sustained-release/bupropion sustained-release for the management of obesity: review of the data to date

Por Caixàs, Assumpta, Albert, Lara, Capel, Ismael, Rigla, Mercedes
Publicado em 2014

“... to lose weight. It is known that eating a healthy diet and exercising regularly can help prevent obesity...”
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The influence of dietary sodium content on the pharmacokinetics and pharmacodynamics of fimasartan

Por Gu, Namyi, Cho, Joo-Youn, Shin, Kwang-Hee, Jang, In-Jin, Rhee, Moo-Yong
Publicado no Drug Des Devel Ther (2016)

“...A low sodium diet enhances the hemodynamic effect of renin–angiotensin system blockers...”
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Dietary arginine silicate inositol complex inhibits periodontal tissue loss in rats with ligature-induced periodontitis

Por Dundar, Serkan, Eltas, Abubekir, Hakki, Sema S, Malkoc, Sıddık, Uslu, M Ozay, Tuzcu, Mehmet, Komorowski, James, Ozercan, I Hanifi, Akdemir, Fatih, Sahin, Kazim
Publicado no Drug Des Devel Ther (2016)

“...The purpose of this study was to induce experimental periodontitis in rats previously fed diets...”
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S-nitroso-N-acetylcysteine attenuates liver fibrosis in experimental nonalcoholic steatohepatitis

Por Mazo, Daniel FC, de Oliveira, Marcelo G, Pereira, Isabel VA, Cogliati, Bruno, Stefano, José T, de Souza, Gabriela FP, Rabelo, Fabíola, Lima, Fabiana R, Alves, Venâncio A Ferreira, Carrilho, Flair J, de Oliveira, Claudia PMS
Publicado em 2013

“... diet and exposed to diethylnitrosamine for 8 weeks. The rats were divided into three groups: SNAC...”
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Nonalcoholic steatohepatitis: emerging targeted therapies to optimize treatment options

Por Milic, Sandra, Mikolasevic, Ivana, Krznaric-Zrnic, Irena, Stanic, Marija, Poropat, Goran, Stimac, Davor, Vlahovic-Palcevski, Vera, Orlic, Lidija
Publicado no Drug Des Devel Ther (2015)

“...Diet and lifestyle changes have led to worldwide increases in the prevalences of obesity...”
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Comparison of oral absorption models for pregabalin: usefulness of transit compartment model

Por Hong, Taegon, Han, Seunghoon, Lee, Jongtae, Jeon, Sangil, Yim, Dong-Seok
Publicado no Drug Des Devel Ther (2016)

“... studies (n=88) of single- or multiple-dose pregabalin (150 mg) were used. Pregabalin was administered...”
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Effects of combined dietary supplementation with fenofibrate and Schisandrae Fructus pulp on lipid and glucose levels and liver function in normal and hypercholesterolemic mice

Por Zhu, Pei-Li, Pan, Si-Yuan, Zhou, Shu-Feng, Zhang, Yi, Wang, Xiao-Yan, Sun, Nan, Chu, Zhu-Sheng, Yu, Zhi-Ling, Ko, Kam-Ming
Publicado no Drug Des Devel Ther (2015)

“...BACKGROUND: Currently, combined therapy using herbs and synthetic drugs has become a feasible...”
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Comparison between 3-Nitrooxyphenyl acetylsalicylate (NO-ASA) and O(2)-(acetylsalicyloxymethyl)-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate (NONO-ASA) as Safe Anti-Inflammatory, An...

Por Chattopadhyay, Mitali, Velazquez, Carlos A., Pruski, April, Nia, Kamran V., Abdellatif, Khaled R., Keefer, Larry K., Kashfi, Khosrow
Publicado em 2010

“... drugs were administered orally at equimolar doses. For antiulcerogenic study, 6 h after administration...”
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Analysis of β-Subunit-dependent GABA(A) Receptor Modulation and Behavioral Effects of Valerenic Acid Derivatives

Por Khom, S., Hintersteiner, J., Luger, D., Haider, M., Pototschnig, G., Mihovilovic, M. D., Schwarzer, C., Hering, S.
Publicado no J Pharmacol Exp Ther (2016)

“... and anticonvulsive effects in mice devoid of sedation, making VA an interesting drug candidate. Here we analyzed β...”
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The mGluR5 Positive Allosteric Modulator CDPPB Does Not Alter Extinction or Contextual Reinstatement of Methamphetamine-Seeking Behavior in Rats

Por Widholm, John J., Gass, Justin T., Cleva, Richard M., Olive, M. Foster
Publicado em 2011

“... with improved pharmacological properties and devoid of potential side effects at higher doses....”
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Dietary arginine silicate inositol complex increased bone healing: histologic and histomorphometric study

Por Yaman, Ferhan, Acikan, Izzet, Dundar, Serkan, Simsek, Sercan, Gul, Mehmet, Ozercan, Ibrahim Hanifi, Komorowski, James, Sahin, Kazim
Publicado no Drug Des Devel Ther (2016)

“... assigned to two groups of 21 rats each. The control group was fed a standard diet for 12 weeks; after...”
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The pharmacological profile and clinical prospects of the oral 5-HT1F receptor agonist lasmiditan in the acute treatment of migraine

Por Reuter, Uwe, Israel, Heike, Neeb, Lars
Publicado no Ther Adv Neurol Disord (2015)

“... antimigraine drugs, which is also reflected by its dose-dependent adverse event profile chiefly including...”
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