Comparison of oral absorption models for pregabalin: usefulness of transit compartment model

Pregabalin is an anticonvulsant used for the treatment of neuropathic pain and partial seizure in adults. The aim of this study was to develop a population pharmacokinetic (PK) model to describe the absorption characteristics of pregabalin given fasted or after meals. Data from five healthy subject...

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Bibliografiske detaljer
Udgivet i:Drug Des Devel Ther
Main Authors: Hong, Taegon, Han, Seunghoon, Lee, Jongtae, Jeon, Sangil, Yim, Dong-Seok
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2016
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5153293/
https://ncbi.nlm.nih.gov/pubmed/27994441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S123318
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