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Saturable human neopterin response to interferon-α assessed by a pharmacokinetic-pharmacodynamic model
BACKGROUND: In this study, we developed a pharmacokinetic (PK)- pharmacodynamic (PD) model of a new sustained release formulation of interferon-α-2a (SR-IFN-α) using the blood concentration of IFN-α and neopterin in order to quantify the magnitude and saturation of neopterin production over time in...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3853247/ https://ncbi.nlm.nih.gov/pubmed/24088361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-240 |
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