Saturable human neopterin response to interferon-α assessed by a pharmacokinetic-pharmacodynamic model

BACKGROUND: In this study, we developed a pharmacokinetic (PK)- pharmacodynamic (PD) model of a new sustained release formulation of interferon-α-2a (SR-IFN-α) using the blood concentration of IFN-α and neopterin in order to quantify the magnitude and saturation of neopterin production over time in...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Jeon, Sangil, Juhn, Jae-Hyeon, Han, Seunghoon, Lee, Jongtae, Hong, Taegon, Paek, Jeongki, Yim, Dong-Seok
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2013
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853247/
https://ncbi.nlm.nih.gov/pubmed/24088361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-240
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