Resultados da pesquisa - (( _ natl computer can now ) OR ((( j natalia comp

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Protein kinase inhibitors selectively block phorbol ester- or forskolin- induced changes in excitability of Aplysia neurons

Por Conn, PJ, Strong, JA, Azhderian, EM, Nairn, AC, Greengard, P, Kaczmarek, LK
Publicado no J Neurosci (1989)

“... changes in bag cell neuronal excitability. We have now found that treatment of bag cell neurons...”
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Distinct intracellular sAC-cAMP domains regulate ER Ca(2+) signaling and OXPHOS function

Por Valsecchi, Federica, Konrad, Csaba, D'Aurelio, Marilena, Ramos-Espiritu, Lavoisier S., Stepanova, Anna, Burstein, Suzanne R., Galkin, Alexander, Magranè, Jordi, Starkov, Anatoly, Buck, Jochen, Levin, Lonny R., Manfredi, Giovanni
Publicado no J Cell Sci (2017)

“... soluble adenylyl cyclase (sAC) regulates oxidative phosphorylation (OXPHOS). We now show that sAC knockout...”
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AKAP79 Interacts with Multiple Adenylyl Cyclase (AC) Isoforms and Scaffolds AC5 and -6 to α-Amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (AMPA) Receptors

Por Efendiev, Riad, Samelson, Bret K., Nguyen, Bao T., Phatarpekar, Prasad V., Baameur, Faiza, Scott, John D., Dessauer, Carmen W.
Publicado em 2010

“... synthesis. We now show that AKAP79 can associate with multiple AC isoforms. The N-terminal regions of AC5...”
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Computation of Large Molecules with the Hartree-Fock Model

Por Clementi, Enrico
Publicado em 1972

“... in the Hartree-Fock energy (correlation energy error) can be easily computed by use of a statistical model...”
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Convolutional networks for fast, energy-efficient neuromorphic computing

Por Esser, Steven K., Merolla, Paul A., Arthur, John V., Cassidy, Andrew S., Appuswamy, Rathinakumar, Andreopoulos, Alexander, Berg, David J., McKinstry, Jeffrey L., Melano, Timothy, Barch, Davis R., di Nolfo, Carmelo, Datta, Pallab, Amir, Arnon, Taba, Brian, Flickner, Myron D., Modha, Dharmendra S.
Publicado no Proc Natl Acad Sci U S A (2016)

“... tasks. Independently, neuromorphic computing has now demonstrated unprecedented energy-efficiency...”
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Computational generation of an annotated gigalibrary of synthesizable, composite peptidic macrocycles

Por Saha, Ishika, Dang, Eric K., Svatunek, Dennis, Houk, Kendall N., Harran, Patrick G.
Publicado no Proc Natl Acad Sci U S A (2020)

“... and far outpaces the capacity of our experimental format. We now describe a computational rendering of our...”
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Folding a protein in a computer: An atomic description of the folding/unfolding of protein A

Por García, Angel E., Onuchic, José N.
Publicado em 2003

“... is now possible. The kinetic bottlenecks for folding can be determined from the thermal ensembles...”
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Control of a two-dimensional movement signal by a noninvasive brain-computer interface in humans

Por Wolpaw, Jonathan R., McFarland, Dennis J.
Publicado em 2004

“...Brain-computer interfaces (BCIs) can provide communication and control to people who are totally...”
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The metabolic/pH sensor soluble adenylyl cyclase is a tumor suppressor protein

Por Ramos-Espiritu, Lavoisier, Diaz, Ana, Nardin, Charlee, Saviola, Anthony J., Shaw, Fiona, Plitt, Tamar, Yang, Xia, Wolchok, Jedd, Pirog, Edyta C., Desman, Garrett, Sboner, Andrea, Zhang, Tuo, Xiang, Jenny, Merghoub, Taha, Levin, Lonny R., Buck, Jochen, Zippin, Jonathan H.
Publicado no Oncotarget (2016)

“...cAMP signaling pathways can both stimulate and inhibit the development of cancer; however...”
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Heritage at War

Publicado em 2024

Assuntos: “...bic Book Industry Communication::J Society & social sciences::JW Warfare & defence...”
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Regulation of nephron water and electrolyte transport by adenylyl cyclases

Por Rieg, Timo, Kohan, Donald E.
Publicado em 2014

“.... As will be described, it is now evident that specific AC isoforms can exert unique effects in the kidney that may have...”
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A new decision sciences for complex systems

Por Lempert, Robert J.
Publicado em 2002

“... ensembles of computational experiments, now make possible systematic comparison of alternative policy...”
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Automated 2D IR spectroscopy using a mid-IR pulse shaper and application of this technology to the human islet amyloid polypeptide

Por Shim, Sang-Hee, Strasfeld, David B., Ling, Yun L., Zanni, Martin T.
Publicado em 2007

“... defined lineshapes. Furthermore, phase cycling can now be employed to largely alleviate background scatter...”
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Protein folding kinetics and thermodynamics from atomistic simulation

Por Piana, Stefano, Lindorff-Larsen, Kresten, Shaw, David E.
Publicado em 2012

“..., but following a slightly different pathway. This work showcases how computer simulation has now developed into a...”
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Receptors for glucocorticosteroid and progesterone recognize distinct features of a DNA regulatory element.

Por von der Ahe, D, Renoir, J M, Buchou, T, Baulieu, E E, Beato, M
Publicado em 1986

“...The chicken lysozyme gene can be induced in oviduct cells by four classes of steroid hormones...”
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Origin of the emergent fragile-to-strong transition in supercooled water

Por Shi, Rui, Russo, John, Tanaka, Hajime
Publicado no Proc Natl Acad Sci U S A (2018)

“...Liquids can be broadly classified into two categories, fragile and strong ones, depending on how...”
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An automated multiplex oligonucleotide synthesizer: development of high-throughput, low-cost DNA synthesis.

Por Lashkari, D A, Hunicke-Smith, S P, Norgren, R M, Davis, R W, Brennan, T
Publicado em 1995

“...An automated oligonucleotide synthesizer has been developed that can simultaneously and rapidly...”
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Ensemble versus single-molecule protein unfolding

Por Day, Ryan, Daggett, Valerie
Publicado em 2005

“... the ensemble behavior of large numbers of molecules. Given the increase in computer power, we now address...”
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Distance-based protein folding powered by deep learning

Por Xu, Jinbo
Publicado no Proc Natl Acad Sci U S A (2019)

“... sampling with fragments. We show that we can accurately predict interresidue distance distribution of a...”
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How amoeboids self-organize into a fruiting body: Multicellular coordination in Dictyostelium discoideum

Por Marée, Athanasius F. M., Hogeweg, Paulien
Publicado em 2001

“... explanation has been produced for this process. Using a computer simulation that we developed, we now...”
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