A Retrospective Survey of HIV Drug Resistance Among Patients 1 Year After Initiation of Antiretroviral Therapy at 4 Clinics in Malawi

Por Wadonda-Kabondo, Nellie, Hedt, Bethany L., van Oosterhout, Joep J., Moyo, Kundai, Limbambala, Eddie, Bello, George, Chilima, Ben, Schouten, Erik, Harries, Anthony, Massaquoi, Moses, Porter, Carol, Weigel, Ralf, Hosseinipour, Mina, Aberle-Grasse, John, Jordan, Michael R., Kabuluzi, Storn, Bennett, Diane E.
Publicado em 2012

Clinical Severity in Lesch-Nyhan Disease: the Role of Residual Enzyme and Compensatory Pathways

Por Fu, Rong, Sutcliffe, Diane, Zhao, Hong, Huang, Xinyi, Schretlen, David J., Benkovic, Steve, Jinnah, H. A.
Publicado no Mol Genet Metab (2014)

Seasonal changes in gene expression represent cell-type composition in whole blood

Por De Jong, Simone, Neeleman, Marjolein, Luykx, Jurjen J., Ten Berg, Maarten J., Strengman, Eric, Den Breeijen, Hanneke H., Stijvers, Leon C., Buizer-Voskamp, Jacobine E., Bakker, Steven C., Kahn, René S., Horvath, Steve, Van Solinge, Wouter W., Ophoff, Roel A.
Publicado em 2014

Novel half-life extended anti-MIF nanobodies protect against endotoxic shock

Por Sparkes, Amanda, De Baetselier, Patrick, Brys, Lea, Cabrito, Inês, Sterckx, Yann G.-J., Schoonooghe, Steve, Muyldermans, Serge, Raes, Geert, Bucala, Richard, Vanlandschoot, Peter, Van Ginderachter, Jo A., Stijlemans, Benoît
Publicado no FASEB J (2018)

Analysis of tumor metabolism reveals mitochondrial glucose oxidation in genetically diverse, human glioblastomas in the mouse brain in vivo

Por Marin-Valencia, Isaac, Yang, Chendong, Mashimo, Tomoyuki, Cho, Steve, Baek, Hyeonman, Yang, Xiao-Li, Rajagopalan, Kartik N., Maddie, Melissa, Vemireddy, Vamsidhara, Zhao, Zhenze, Cai, Ling, Good, Levi, Tu, Benjamin P., Hatanpaa, Kimmo J., Mickey, Bruce E., Matés, José M., Pascual, Juan M., Maher, Elizabeth A., Malloy, Craig R., DeBerardinis, Ralph J., Bachoo, Robert M.
Publicado em 2012

The Dynamics of Compound, Transcript, and Protein Effects After Treatment With 2OMePS Antisense Oligonucleotides in mdx Mice

Por Verhaart, Ingrid E C, van Vliet-van den Dool, Laura, Sipkens, Jessica A, de Kimpe, Sjef J, Kolfschoten, Ingrid G M, van Deutekom, Judith C T, Liefaard, Lia, Ridings, Jim E, Hood, Steve R, Aartsma-Rus, Annemieke
Publicado em 2014

Calcium Oxalate Stone Formation in the Inner Ear as a Result of an Slc26a4 Mutation

Por Dror, Amiel A., Politi, Yael, Shahin, Hashem, Lenz, Danielle R., Dossena, Silvia, Nofziger, Charity, Fuchs, Helmut, Hrabé de Angelis, Martin, Paulmichl, Markus, Weiner, Steve, Avraham, Karen B.
Publicado em 2010

Genetic diseases conferring resistance to infectious diseases

Por Withrock, Isabelle C., Anderson, Stephen J., Jefferson, Matthew A., McCormack, Garrett R., Mlynarczyk, Gregory S.A., Nakama, Aron, Lange, Jennifer K., Berg, Carrie A., Acharya, Sreemoyee, Stock, Matthew L., Lind, Melissa S., Luna, K.C., Kondru, Naveen C., Manne, Sireesha, Patel, Bhavika B., de la Rosa, Bierlein M., Huang, Kuei-Pin, Sharma, Shaunik, Hu, Hilary Z., Kanuri, Sri Harsha, Carlson, Steve A.
Publicado no Genes Dis (2015)

Human Genetics in Rheumatoid Arthritis Guides a High-Throughput Drug Screen of the CD40 Signaling Pathway

Por Li, Gang, Diogo, Dorothée, Wu, Di, Spoonamore, Jim, Dancik, Vlado, Franke, Lude, Kurreeman, Fina, Rossin, Elizabeth J., Duclos, Grant, Hartland, Cathy, Zhou, Xuezhong, Li, Kejie, Liu, Jun, De Jager, Philip L., Siminovitch, Katherine A., Zhernakova, Alexandra, Raychaudhuri, Soumya, Bowes, John, Eyre, Steve, Padyukov, Leonid, Gregersen, Peter K., Worthington, Jane, Gupta, Namrata, Clemons, Paul A., Stahl, Eli, Tolliday, Nicola, Plenge, Robert M.
Publicado em 2013

Chemical genetics of Plasmodium falciparum

Por Guiguemde, W. Armand, Shelat, Anang A., Bouck, David, Duffy, Sandra, Crowther, Gregory J., Davis, Paul H., Smithson, David C., Connelly, Michele, Clark, Julie, Zhu, Fangyi, Jiménez-Díaz, María B, Martinez, María S, Wilson, Emily B., Tripathi, Abhai K., Gut, Jiri, Sharlow, Elizabeth R., Bathurst, Ian, El Mazouni, Farah, Fowble, Joseph W, Forquer, Isaac, McGinley, Paula L, Castro, Steve, Angulo-Barturen, Iñigo, Ferrer, Santiago, Rosenthal, Philip J., DeRisi, Joseph L, Sullivan, David J., Lazo, John S., Roos, David S., Riscoe, Michael K., Phillips, Margaret A., Rathod, Pradipsinh K., Van Voorhis, Wesley C., Avery, Vicky M, Guy, R. Kiplin
Publicado em 2010

Sequencing the mouse Y chromosome reveals convergent gene acquisition and amplification on both sex chromosomes

Por Soh, Y.Q. Shirleen, Alföldi, Jessica, Pyntikova, Tatyana, Brown, Laura G., Graves, Tina, Minx, Patrick J., Fulton, Robert S., Kremitzki, Colin, Koutseva, Natalia, Mueller, Jacob L., Rozen, Steve, Hughes, Jennifer F., Owens, Elaine, Womack, James E., Murphy, William J., Cao, Qing, de Jong, Pieter, Warren, Wesley C., Wilson, Richard K., Skaletsky, Helen, Page, David C.
Publicado no Cell (2014)

Aberrant activation of Notch signaling inhibits PROX1 activity to enhance the malignant behavior of thyroid cancer cells

Por Choi, Dongwon, Ramu, Swapnika, Park, Eunkyung, Jung, Eunson, Yang, Sara, Jung, Wonhyeuk, Choi, Inho, Lee, Sunju, Kim, Kyu Eui, Seong, Young Jin, Hong, Mingu, Daghlian, George H., Kim, Daniel, Shin, Eugene, Seo, Jung In, Khatchadourian, Vicken, Zou, Mengchen, Li, Wei, De Filippo, Roger E., Kokorowski, Paul J., Chang, Andy Y., Kim, Steve S., Santin, Ana, Furlanetto, Tania, Shin, Sung S., Li, Meng, Chen, Yibu, Wong, Alex K., Koh, Chester J., Geliebter, Jan, Hong, Young-Kwon
Publicado no Cancer Res (2015)

Protein Tyrosine Phosphatase-N13 Promotes Myofibroblast Resistance to Apoptosis in Idiopathic Pulmonary Fibrosis

Por Bamberg, Alison, Redente, Elizabeth F., Groshong, Steve D., Tuder, Rubin M., Cool, Carlyne D., Keith, Rebecca C., Edelman, Benjamin L., Black, Bart P., Cosgrove, Gregory P., Wynes, Murry W., Curran-Everett, Douglas, De Langhe, Stijn, Ortiz, Luis A., Thorburn, Andrew, Riches, David W. H.
Publicado no Am J Respir Crit Care Med (2018)

Mouse large-scale phenotyping initiatives: overview of the European Mouse Disease Clinic (EUMODIC) and of the Wellcome Trust Sanger Institute Mouse Genetics Project

Por Ayadi, Abdel, Birling, Marie-Christine, Bottomley, Joanna, Bussell, James, Fuchs, Helmut, Fray, Martin, Gailus-Durner, Valérie, Greenaway, Simon, Houghton, Richard, Karp, Natasha, Leblanc, Sophie, Lengger, Christoph, Maier, Holger, Mallon, Ann-Marie, Marschall, Susan, Melvin, David, Morgan, Hugh, Pavlovic, Guillaume, Ryder, Ed, Skarnes, William C., Selloum, Mohammed, Ramirez-Solis, Ramiro, Sorg, Tania, Teboul, Lydia, Vasseur, Laurent, Walling, Alison, Weaver, Tom, Wells, Sara, White, Jacqui K., Bradley, Allan, Adams, David J., Steel, Karen P., Hrabě de Angelis, Martin, Brown, Steve D., Herault, Yann
Publicado em 2012

Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease

Por Folkersen, Lasse, Fauman, Eric, Sabater-Lleal, Maria, Strawbridge, Rona J., Frånberg, Mattias, Sennblad, Bengt, Baldassarre, Damiano, Veglia, Fabrizio, Humphries, Steve E., Rauramaa, Rainer, de Faire, Ulf, Smit, Andries J., Giral, Philippe, Kurl, Sudhir, Mannarino, Elmo, Enroth, Stefan, Johansson, Åsa, Enroth, Sofia Bosdotter, Gustafsson, Stefan, Lind, Lars, Lindgren, Cecilia, Morris, Andrew P., Giedraitis, Vilmantas, Silveira, Angela, Franco-Cereceda, Anders, Tremoli, Elena, Gyllensten, Ulf, Ingelsson, Erik, Brunak, Søren, Eriksson, Per, Ziemek, Daniel, Hamsten, Anders, Mälarstig, Anders
Publicado no PLoS Genet (2017)

Global Panel of HIV-1 Env Reference Strains for Standardized Assessments of Vaccine-Elicited Neutralizing Antibodies

Por deCamp, Allan, Hraber, Peter, Bailer, Robert T., Seaman, Michael S., Ochsenbauer, Christina, Kappes, John, Gottardo, Raphael, Edlefsen, Paul, Self, Steve, Tang, Haili, Greene, Kelli, Gao, Hongmei, Daniell, Xiaoju, Sarzotti-Kelsoe, Marcella, Gorny, Miroslaw K., Zolla-Pazner, Susan, LaBranche, Celia C., Mascola, John R., Korber, Bette T., Montefiori, David C.
Publicado em 2014

Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation

Por Alicia Mayeuf-Louchart, Steve Lancel, Yasmine Sebti, Benoit Pourcet, Anne Loyens, Stéphane Delhaye, Christian Duhem, Justine Beauchamp, Lise Ferri, Quentin Thorel, Alexis Boulinguiez, Mathilde Zecchin, Julie Dubois-Chevalier, Jérôme Eeckhoute, Logan T. Vaughn, Peter J. Roach, Christian Dani, Bartholomew A. Pederson, Stéphane D. Vincent, Bart Staels, Hélène Duez
Publicado em 2019-11-01

Genetics of rheumatoid arthritis contributes to biology and drug discovery

Por Okada, Yukinori, Wu, Di, Trynka, Gosia, Raj, Towfique, Terao, Chikashi, Ikari, Katsunori, Kochi, Yuta, Ohmura, Koichiro, Suzuki, Akari, Yoshida, Shinji, Graham, Robert R., Manoharan, Arun, Ortmann, Ward, Bhangale, Tushar, Denny, Joshua C., Carroll, Robert J., Eyler, Anne E., Greenberg, Jeffrey D., Kremer, Joel M., Pappas, Dimitrios A., Jiang, Lei, Yin, Jian, Ye, Lingying, Su, Ding-Feng, Yang, Jian, Xie, Gang, Keystone, Ed, Westra, Harm-Jan, Esko, Tõnu, Metspalu, Andres, Zhou, Xuezhong, Gupta, Namrata, Mirel, Daniel, Stahl, Eli A., Diogo, Dorothée, Cui, Jing, Liao, Katherine, Guo, Michael H., Myouzen, Keiko, Kawaguchi, Takahisa, Coenen, Marieke J.H., van Riel, Piet L.C.M., van de Laar, Mart A.F.J., Guchelaar, Henk-Jan, Huizinga, Tom W.J., Dieudé, Philippe, Mariette, Xavier, Bridges, S. Louis, Zhernakova, Alexandra, Toes, Rene E.M., Tak, Paul P., Miceli-Richard, Corinne, Bang, So-Young, Lee, Hye-Soon, Martin, Javier, Gonzalez-Gay, Miguel A., Rodriguez-Rodriguez, Luis, Rantapää-Dahlqvist, Solbritt, Ärlestig, Lisbeth, Choi, Hyon K., Kamatani, Yoichiro, Galan, Pilar, Lathrop, Mark, Eyre, Steve, Bowes, John, Barton, Anne, de Vries, Niek, Moreland, Larry W., Criswell, Lindsey A., Karlson, Elizabeth W., Taniguchi, Atsuo, Yamada, Ryo, Kubo, Michiaki, Liu, Jun S., Bae, Sang-Cheol, Worthington, Jane, Padyukov, Leonid, Klareskog, Lars, Gregersen, Peter K., Raychaudhuri, Soumya, Stranger, Barbara E., De Jager, Philip L., Franke, Lude, Visscher, Peter M., Brown, Matthew A., Yamanaka, Hisashi, Mimori, Tsuneyo, Takahashi, Atsushi, Xu, Huji, Behrens, Timothy W., Siminovitch, Katherine A., Momohara, Shigeki, Matsuda, Fumihiko, Yamamoto, Kazuhiko, Plenge, Robert M.
Publicado em 2013

Development of synchronous VHL syndrome tumors reveals contingencies and constraints to tumor evolution

Por Fisher, Rosalie, Horswell, Stuart, Rowan, Andrew, Salm, Maximilian P, de Bruin, Elza C, Gulati, Sakshi, McGranahan, Nicholas, Stares, Mark, Gerlinger, Marco, Varela, Ignacio, Crockford, Andrew, Favero, Francesco, Quidville, Virginie, André, Fabrice, Navas, Carolina, Grönroos, Eva, Nicol, David, Hazell, Steve, Hrouda, David, O’Brien, Tim, Matthews, Nik, Phillimore, Ben, Begum, Sharmin, Rabinowitz, Adam, Biggs, Jennifer, Bates, Paul A, McDonald, Neil Q, Stamp, Gordon, Spencer-Dene, Bradley, Hsieh, James J, Xu, Jianing, Pickering, Lisa, Gore, Martin, Larkin, James, Swanton, Charles
Publicado em 2014

Somatic mutations reveal asymmetric cellular dynamics in the early human embryo

Por Ju, Young Seok, Martincorena, Inigo, Gerstung, Moritz, Petljak, Mia, Alexandrov, Ludmil B, Rahbari, Raheleh, Wedge, David C, Davies, Helen R, Ramakrishna, Manasa, Fullam, Anthony, Martin, Sancha, Alder, Christopher, Patel, Nikita, Gamble, Steve, O’Meara, Sarah, Giri, Dilip D, Sauer, Torril, Pinder, Sarah E, Purdie, Colin A, Borg, Åke, Stunnenberg, Henk, van de Vijver, Marc, Tan, Benita K.T., Caldas, Carlos, Tutt, Andrew, Ueno, Naoto T, van’t Veer, Laura J, Martens, John W. M., Sotiriou, Christos, Knappskog, Stian, Span, Paul N., Lakhani, Sunil R., Eyfjörd, Jórunn Erla, Børresen-Dale, Anne-Lise, Richardson, Andrea, Thompson, Alastair M., Viari, Alain, Hurles, Matthew E, Nik-Zainal, Serena, Campbell, Peter J, Stratton, Michael R
Publicado no Nature (2017)