Resultados da pesquisa - ((((drug dnaal) OR (drug does))) OR (drug dna)) devel ther~

1

Quantum mechanics implementation in drug-design workflows: does it really help?

Por Arodola, Olayide A, Soliman, Mahmoud ES
Publicado no Drug Des Devel Ther (2017)

“... them into drug-design and -discovery workflows while trying to answer a critical question: are QM-based...”
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Quantum mechanics implementation in drug-design workflows: does it really help? [Corrigendum]

Publicado no Drug Des Devel Ther (2017)

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Drug design with Cdc7 kinase: a potential novel cancer therapy target

Por Sawa, Masaaki, Masai, Hisao
Publicado em 2009

“..., accumulates DNA damage, and induces p53-independent cell death, but the same treatment in normal cells does...”
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Anesthetic drug midazolam inhibits cardiac human ether-à-go-go-related gene channels: mode of action

Por Vonderlin, Nadine, Fischer, Fathima, Zitron, Edgar, Seyler, Claudia, Scherer, Daniel, Thomas, Dierk, Katus, Hugo A, Scholz, Eberhard P
Publicado no Drug Des Devel Ther (2015)

“... and potassium channels. So far, the effects of midazolam on cardiac human ether-à-go-go-related gene (hERG...”
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Pharmacokinetic interactions between glimepiride and rosuvastatin in healthy Korean subjects: does...

Por Kim, Choon Ok, Oh, Eun Sil, Kim, Hohyun, Park, Min Soo
Publicado no Drug Des Devel Ther (2017)

“... showed that both glimepiride and rosuvastatin did not interact with each other and had tolerable safety...”
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Cardioprotection with halogenated gases: how does it occur?

Por Guerrero-Orriach, Jose Luis, Escalona Belmonte, Juan Jose, Ramirez Fernandez, Alicia, Ramirez Aliaga, Marta, Rubio Navarro, Manuel, Cruz Mañas, Jose
Publicado no Drug Des Devel Ther (2017)

“... of the administered drug and the duration of the administration itself. Triggers for postconditioning...”
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Pharmacokinetic interactions between glimepiride and rosuvastatin in healthy Korean subjects: does...

Por Thakkar, Disha, Dash, Ranjeet Prasad
Publicado no Drug Des Devel Ther (2017)

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N-(3-hydroxymethyl-β-carboline-1-yl-ethyl- 2-yl)-l-Phe: development toward a nanoscaled antitumor drug capable of treating complicated thrombosis and inflammation

Por Wu, Jianhui, Zhao, Ming, Wang, Yuji, Wang, Yaonan, Zhu, Haimei, Zhao, Shurui, Gui, Lin, Zhang, Xiaoyi, Peng, Shiqi
Publicado no Drug Des Devel Ther (2017)

“... S180 mice, and has a minimal effective dose of 2 nmol/kg per day. At 200 nmol/kg per day, HMCEF does...”
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Paliperidone extended-release: does it have a place in antipsychotic therapy?

Por Gahr, Maximilian, Kölle, Markus A, Schönfeldt-Lecuona, Carlos, Lepping, Peter, Freudenmann, Roland W
Publicado em 2011

“... pharmacological profile, including single dosing, predominantly renal excretion, low drug–drug interaction risk...”
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Organelle targeting: third level of drug targeting

Por Sakhrani, Niraj M, Padh, Harish
Publicado em 2013

“...Drug discovery and drug delivery are two main aspects for treatment of a variety of disorders...”
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Magnesium: does it reduce ischemia/reperfusion injury in an adnexal torsion rat model?

Por Celik Kavak, Ebru, Gulcu Bulmus, Funda, Bulmus, Ozgur, Kavak, Salih Burcin, Kocaman, Nevin
Publicado no Drug Des Devel Ther (2018)

“... and the other for biochemical analyses. RESULTS: In the torsion–detorsion group, all the histopathological...”
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Does fesoterodine have a role in the treatment of poorly managed patients with overactive bladder?

Por Morris, Vikky, Wagg, Adrian
Publicado em 2014

“... be at risk of receiving poor treatment because of either multimorbidity or complex polypharmacy....”
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Does remifentanil attenuate renal ischemia–reperfusion injury better than dexmedetomidine in rat kidney?

Por Erkılıç, E, Kesimci, E, Alaybeyoğlu, F, Kılınç, I, Tural, R, Yazgan, A, Gümüş, T, Sepici Dinçel, A, Dumlu, EG, Kanbak, O
Publicado no Drug Des Devel Ther (2017)

“..., and T2. The plasma NGAL levels at T2 in group S were significantly higher than those at T2 in group DEX...”
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Does celecoxib inhibit agomelatine metabolism via CYP2C9 or CYP1A2?

Por Yasar, Umit
Publicado no Drug Des Devel Ther (2018)

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Defective DNA repair mechanisms in prostate cancer: impact of olaparib

Por De Felice, Francesca, Tombolini, Vincenzo, Marampon, Francesco, Musella, Angela, Marchetti, Claudia
Publicado no Drug Des Devel Ther (2017)

“... that is intensely linked to molecular genetic alterations, especially DNA-repair defects. Germline breast cancer 1...”
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Anticancer, antioxidant activities, and DNA affinity of novel monocationic bithiophenes and analogues

Por Ismail, Mohamed A, Arafa, Reem K, Youssef, Magdy M, El-Sayed, Wael M
Publicado em 2014

“... in antiproliferative activity. On the other hand, DNA studies demonstrated that these monoamidine bichalcophenes have...”
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DNA stabilization by the upregulation of estrogen signaling in BRCA gene mutation carriers

Por Suba, Zsuzsanna
Publicado no Drug Des Devel Ther (2015)

“... of the BRCA1/2 genes may liberate the proliferative effects of estrogen signaling, which provokes DNA damage...”
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Concomitant food intake does not affect the efficacy of entecavir in chronic hepatitis B patients...

Por Cho, Eun Ju, Yu, Su Jong, Kwon, So Young, Kim, Ji-Hoon, Kim, Do Young, Kim, Won, Lee, June Sung, Lee, Jin Woo, Lee, Youn Jae, Chae, Hee Bok, Yoon, Jung-Hwan
Publicado no Drug Des Devel Ther (2018)

“... and showed a serum HBV DNA level of <20 IU/mL were randomized to take entecavir either under the fasted...”
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Preparation, characterization, and potential application of chitosan, chitosan derivatives, and chitosan metal nanoparticles in pharmaceutical drug delivery

Por Ahmed, Tarek A, Aljaeid, Bader M
Publicado no Drug Des Devel Ther (2016)

“..., vaccines, DNA, and drugs for parenteral and nonparenteral administration. Therapeutic agent-loaded chitosan...”
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YB-1 modulates the drug resistance of glioma cells by activation of MDM2/p53 pathway

Por Tong, Hui, Zhao, Kai, Zhang, Jingyu, Zhu, Jinxin, Xiao, Jianqi
Publicado no Drug Des Devel Ther (2019)

“... by transfection of pcDNA-YB-1 and siRNA against YB-1, respectively. Cell viability was performed by CCK8 assay...”
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