Pharmacokinetic interactions between glimepiride and rosuvastatin in healthy Korean subjects: does the SLCO1B1 or CYP2C9 genetic polymorphism affect these drug interactions?

To improve cardiovascular outcomes, dyslipidemia in patients with diabetes needs to be treated. Thus, these patients are likely to take glimepiride and rosuvastatin concomitantly. Therefore, this study aimed to evaluate the pharmacokinetic (PK) interactions between these two drugs in healthy males a...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Kim, Choon Ok, Oh, Eun Sil, Kim, Hohyun, Park, Min Soo
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330189/
https://ncbi.nlm.nih.gov/pubmed/28260863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S129586
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