Resultados da pesquisa - ((((drug de) OR (drug dose))v) OR (((drug de) OR (drug dose)))) ((devel ther) OR (model theory))

1

Changing the face of hepatitis C management – the design and development of sofosbuvir

Por Noell, Bennett C, Besur, Siddesh V, deLemos, Andrew S
Publicado no Drug Des Devel Ther (2015)

“... with another DAA such as the NS3-4A protease inhibitor, simeprevir, or the NS5A replication complex inhibitors...”
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2

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Optimal control strategies of eradicating invisible glioblastoma cells after conventional surgery

Por de los Reyes V, Aurelio A., Jung, Eunok, Kim, Yangjin
Publicado no J R Soc Interface (2015)

“... of these cancer cells at the surgical site. The model also considers the effect of a drug that blocks inhibitive...”
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3

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Design of study without drugs—a Surinamese school-based drug-prevention program for adolescents

Por Ishaak, Fariel, de Vries, Nanne Karel, van der Wolf, Kees
Publicado no BMC Public Health (2015)

“...-based program—Study without Drugs—for adolescents in junior secondary schools in Suriname based...”
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4

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Theories of Addiction: Methamphetamine Users’ Explanations for Continuing Drug Use and Relapse

Por Newton, Thomas F., De La Garza, Richard, Kalechstein, Ari D., Tziortzis, Desey, Jacobsen, Caitlin A.
Publicado em 2009

“...A variety of preclinical models have been constructed to emphasize unique aspects of addiction-like...”
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5

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Efficacy and safety of a fixed-dose combination of nimesulide/pantoprazole compared to naproxen...

Por Scheinberg, Morton, Pott Júnior, Henrique, Macêdo, Eduardo de Almeida, Bocchi de Oliveira, Monalisa Fernanda, Ecclissato, Christina, Amazonas, Roberto Bleuel
Publicado no Drug Des Devel Ther (2018)

“...PURPOSE: This study investigated the safety and efficacy of fixed-dose combination tablets...”
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6

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Molecular Dynamics Simulation Studies of the Wild-Type, I21V, and I16T Mutants of Isoniazid...

Por Schroeder, Evelyn Koeche, Basso, Luiz Augusto, Santos, Diógenes Santiago, Norberto de Souza, Osmar
Publicado em 2005

Assuntos: “...Biophysical Theory and Modeling...”
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7

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Theoretical Study of the Adsorption Process of Antimalarial Drugs into Acrylamide-Base Hydrogel Model Using DFT Methods: The First Approach to the Rational Design of a Controlled Drug Delivery System

Por Eliceo Cortes, Edgar Márquez, José R. Mora, Esneyder Puello, Norma Rangel, Aldemar De Moya, Jorge Trilleras
Publicado em 2019-06-01

Assuntos: “...computational modeling...”
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8

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Efficacy of the small molecule inhibitor of Lipid II BAS00127538 against Acinetobacter baumannii

Por de Leeuw, Erik PH
Publicado em 2014

“... compound that targets Lipid II is described that acts against multi-drug resistant isolates of A. baumannii...”
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9

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Effect of renal impairment on the pharmacokinetics of prucalopride: a single- dose open-label Phase I study

Por Smith, William B, Mannaert, Erik, Verhaeghe, Tom, Kerstens, René, Vandeplassche, Lieve, Van de Velde, Vera
Publicado em 2012

“...)), and severe RI (≤24 mL/min/1.73 m(2)). All received a single oral dose of prucalopride 2 mg. RESULTS: Thirty...”
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10

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The role of taxanes in triple-negative breast cancer: literature review

Por Mustacchi, Giorgio, De Laurentiis, Michelino
Publicado no Drug Des Devel Ther (2015)

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Role of Statistical Random-Effects Linear Models in Personalized Medicine

Por Diaz, Francisco J, Yeh, Hung-Wen, de Leon, Jose
Publicado em 2012

“... developments show that random-effects linear models may provide a solid theoretical framework for drug dosage...”
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12

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Modeling dose-response microarray data in early drug development experiments using R order-restricted analysis of microarray data /

Por Lin, Dan., Shkedy, Ziv., Yekutieli, Daniel., Amaratunga, Dhammika., Bijnens, Luc.
Publicado em 2012

“... datasets from early drug development experiments. Introduction -- Part I: Dose-response Modeling...”
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Livro

13

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Hologram quantitative structure–activity relationship and comparative molecular field analysis studies within a series of tricyclic phthalimide HIV-1 integrase inhibitors

Por de Oliveira Magalhães, Uiaran, de Souza, Alessandra Mendonça Teles, Albuquerque, Magaly Girão, de Brito, Monique Araújo, Bello, Murilo Lamim, Cabral, Lucio Mendes, Rodrigues, Carlos Rangel
Publicado em 2013

“... immunodeficiency virus (HIV). Treatment with antiretroviral drugs is the best option for viral suppression...”
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14

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Profile of pridopidine and its potential in the treatment of Huntington disease: the evidence to date

Por Squitieri, Ferdinando, de Yebenes, Justo Garcia
Publicado no Drug Des Devel Ther (2015)

“... of patients with HD. More recently, the analysis of HD models (ie, in vitro and in mice) highlighted...”
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15

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Antibiotic-modifying activity of riachin, a non-cyanogenic cyanoglycoside extracted from Bauhinia pentandra

Por de Farias, Pablo Antonio Maia, Figueredo, Fernando Gomes, Lucas, Aline Maria Brito, de Moura, Rafael Barbosa, Coutinho, Henrique Douglas Melo, da Silva, Tania Maria Sarmento, Martin, Ana Luiza de Aguiar Rocha, Fonteles, Marta Maria de França
Publicado no Drug Des Devel Ther (2015)

“... in the drug dose required and possibly in consequent adverse events for patients....”
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16

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Cholesterol confusion and statin controversy

Por DuBroff, Robert, de Lorgeril, Michel
Publicado no World J Cardiol (2015)

“... of cholesterol-lowering statin drugs are debatable. In particular, whether statins actually decrease cardiac...”
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17

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Bioequivalence of a biosimilar enoxaparin sodium to Clexane(®) after single 100 mg subcutaneous dose: results of a randomized, double-blind, crossover study in healthy volunteers

Por Martínez González, Javier, Monreal, Mayte, Ayani Almagia, Ignacio, Llaudó Garín, Jordi, Ochoa Díaz de Monasterioguren, Lourdes, Gutierro Adúriz, Ibón
Publicado no Drug Des Devel Ther (2018)

“... enoxaparin to the reference drug, and to assess its safety and tolerability in healthy volunteers. PATIENTS...”
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18

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Novel Approaches for Visualizing and Analyzing Dose-Timing Data from Electronic Drug Monitors...

Por Gill, Christopher J., DeSilva, Mary Bachman, Hamer, Davidson H., Keyi, Xu, Wilson, Ira B., Sabin, Lora
Publicado no AIDS Behav (2015)

“... models to capture and analyze dose timing data collected longitudinally with electronic drug monitors...”
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Negociando a saúde e autonomia: exclusividade de dados, políticas de saúde e acesso a inovações farmacêuticas

Por Menezes, Henrique Zeferino de, Paranhos, Julia, Torres, Ricardo Lobato, Borges, Luciana Correia, Falcão, Daniela de Santana, Lima, Gustavo Soares Felix
Publicado em 2023

“...O artigo analisa a disputa pela difusão internacional da exclusividade de dados como forma de...”
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Online

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Optical Absorption of the Antitrypanocidal Drug Benznidazole in Water

Por Bezerra, Eveline M., Bezerra-Neto, João R., Sales, Francisco A. M., dos Santos, Ricardo P., Martins, Alice M. C., de Lima-Neto, Pedro, Caetano, Ewerton W. S., Albuquerque, Eudenilson L., Freire, Valder N.
Publicado no Molecules (2014)

“....60, and 5.76 eV. Benznidazole electronic transitions were obtained after density functional theory (DFT...”
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