Resultados da pesquisa - (((( j cantero nerve van dis ) OR ( i gene underlie c dis ))) OR ( j metal reserves system dis ))*

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1

Identifying Potential Therapeutic Targets of Methicillin-resistant Staphylococcus aureus Through in Vivo Proteomic Analysis

Identifying Potential Therapeutic Targets of Methicillin-resistant Staphylococcus aureus Through in Vivo Proteomic Analysis

Por Diep, Binh An, Phung, Qui, Date, Shailesh, Arnott, David, Bakalarski, Corey, Xu, Min, Nakamura, Gerald, Swem, Danielle L., Alexander, Mary Kate, Le, Hoan N., Mai, Thuy T., Tan, Man-Wah, Brown, Eric J., Nishiyama, Mireille
Publicado em 2014

“... murine systemic infection. Results. The majority of the in vivo-expressed surface-associated proteins...”
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2

Engineered human pluripotent stem cell-derived cardiac cells and tissues for electrophysiological studies

Engineered human pluripotent stem cell-derived cardiac cells and tissues for electrophysiological studies

Por Lieu, Deborah K., Turnbull, Irene C., Costa, Kevin D., Li, Ronald A.
Publicado no Drug Discov Today Dis Models (2012)

“... reasons. As such, our understanding of the mechanisms that underlie the physiological...”
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3

Possible effects of EXT2 on mesenchymal differentiation - lessons from the zebrafish

Possible effects of EXT2 on mesenchymal differentiation - lessons from the zebrafish

Por Wiweger, Malgorzata I, de Andrea, Carlos E, Scheepstra, Karel W F, Zhao, Zhe, Hogendoorn, Pancras C W
Publicado em 2014

“...BACKGROUND: Mutations in the EXT genes disrupt polymerisation of heparan sulphates (HS) and lead...”
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4

Vitamin D receptor polymorphism rs2228570 is significantly associated with risk of dyslipidemia and serum LDL levels in Chinese Han population

Vitamin D receptor polymorphism rs2228570 is significantly associated with risk of dyslipidemia and serum LDL levels in Chinese Han population

Por Jia, Jian, Tang, Yayu, Shen, Chong, Zhang, Ning, Ding, Haixia, Zhan, Yiyang
Publicado no Lipids Health Dis (2018)

“...BACKGROUND: The goal of this study was to determine if vitamin D receptor (VDR) gene polymorphisms...”
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5

Thrombotic responses to coronary stents, bioresorbable scaffolds and the Kounis hypersensitivity-associated acute thrombotic syndrome

Thrombotic responses to coronary stents, bioresorbable scaffolds and the Kounis hypersensitivity-associated acute thrombotic syndrome

Por Kounis, Nicholas G., Koniari, Ioanna, Roumeliotis, Anastasios, Tsigas, Grigorios, Soufras, George, Grapsas, Nicholas, Davlouros, Periklis, Hahalis, George
Publicado no J Thorac Dis (2017)

“.... Plain balloon angioplasty, bare metal stents, first and second generation drug-eluting stents...”
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6

The prostaglandin EP1 receptor potentiates kainate receptor activation via a protein kinase C pathway and exacerbates status epilepticus

The prostaglandin EP1 receptor potentiates kainate receptor activation via a protein kinase C pathway and exacerbates status epilepticus

Por Rojas, Asheebo, Gueorguieva, Paoula, Lelutiu, Nadia, Quan, Yi, Shaw, Renee, Dingledine, Raymond
Publicado em 2014

“.... Global ablation of the EP1 gene in mice (EP1-KO) had no effect on seizure threshold after kainate...”
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7

“Neuronal and glia abnormalities in Tsc1-deficient forebrain and partial rescue by rapamycin”

“Neuronal and glia abnormalities in Tsc1-deficient forebrain and partial rescue by rapamycin”

Por Carson, Robert P., Van Nielen, Dominic L., Winzenburger, Peggy A., Ess, Kevin C.
Publicado em 2011

“... in TSC by inactivating the mouse Tsc1 gene in embryonic neural progenitor cells. This strategy permits...”
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8

Selective glucocorticoid receptor translational isoforms reveal glucocorticoid-induced apoptotic transcriptomes

Selective glucocorticoid receptor translational isoforms reveal glucocorticoid-induced apoptotic transcriptomes

Por Wu, I, Shin, S C, Cao, Y, Bender, I K, Jafari, N, Feng, G, Lin, S, Cidlowski, J A, Schleimer, R P, Lu, N Z
Publicado em 2013

“... in mitogen-activated primary T cells and DEX treatment induced GR-C target genes in activated T cells. Cell...”
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9

Association of UBQLN1 mutation with Brown-Vialetto-Van Laere syndrome but not typical ALS

Association of UBQLN1 mutation with Brown-Vialetto-Van Laere syndrome but not typical ALS

Por González-Pérez, Paloma, Lu, Yubing, Chian, Ru-Ju, Sapp, Peter C., Tanzi, Rudolph E., Bertram, Lars, McKenna-Yasek, Diane, Gao, Fen-Biao, Brown, Robert H.
Publicado no Neurobiol Dis (2012)

“...Genetic variants in UBQLN1 gene have been linked to neurodegeneration and mutations in UBQLN2 have...”
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10

BAG3: a multifaceted protein that regulates major cell pathways

BAG3: a multifaceted protein that regulates major cell pathways

Por Rosati, A, Graziano, V, De Laurenzi, V, Pascale, M, Turco, M C
Publicado em 2011

“... of heat shock factor 1 on bag3 gene promoter. In addition to the BAG domain, BAG3 contains also a WW...”
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11

Androgen receptor-mediated apoptosis in bovine testicular induced pluripotent stem cells in response to phthalate esters

Androgen receptor-mediated apoptosis in bovine testicular induced pluripotent stem cells in response to phthalate esters

Por Wang, S-W, Wang, S S-W, Wu, D-C, Lin, Y-C, Ku, C-C, Wu, C-C, Chai, C-Y, Lee, J-N, Tsai, E-M, Lin, C-LS, Yang, R-C, Ko, Y-C, Yu, H-S, Huo, C, Chuu, C-P, Murayama, Y, Nakamura, Y, Hashimoto, S, Matsushima, K, Jin, C, Eckner, R, Lin, C-S, Saito, S, Yokoyama, K K
Publicado em 2013

“... of stemness genes and pluripotency. The iPSCs were used to assess the apoptosis activity following exposure...”
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12

Adolescent cannabis exposure interacts with mutant DISC1 to produce impaired adult emotional memory

Adolescent cannabis exposure interacts with mutant DISC1 to produce impaired adult emotional memory

Por Ballinger, Michael D., Saito, Atsushi, Abazyan, Bagrat, Taniguchi, Yu, Huang, Ching-Hsun, Ito, Koki, Zhu, Xiaolei, Segal, Hadar, Jaaro-Peled, Hanna, Sawa, Akira, Mackie, Ken, Pletnikov, Mikhail V., Kamiya, Atsushi
Publicado no Neurobiol Dis (2015)

“... expression of DN-DISC1 or adolescent Δ(9)-THC treatment. Notably, elevation of c-Fos expression evoked...”
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13

Pharmacogenomic analysis of retinoic-acid induced dyslipidemia in congenic rat model

Pharmacogenomic analysis of retinoic-acid induced dyslipidemia in congenic rat model

Por Krupková, Michaela, Liška, František, Šedová, Lucie, Křenová, Drahomíra, Křen, Vladimír, Šeda, Ondřej
Publicado no Lipids Health Dis (2014)

“... have identified a network with major nodes (including Sirt3, Il1b, Cpt1b and Pparg) likely to underlie...”
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14

Asthma and airways collapse in two heritable disorders of connective tissue

Asthma and airways collapse in two heritable disorders of connective tissue

Por Morgan, A W, Pearson, S B, Davies, S, Gooi, H C, Bird, H A
Publicado em 2007

“... symptoms (HMS: OR 2.4, 95% CI 1.4–4.1, p = 0.002; EDS: OR 3.1, 95% CI 1.8–5.2, p<0.001) and atopy (HMS...”
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15

A bacterial metabolite induces glutathione-tractable proteostatic damage, proteasomal disturbances, and PINK1-dependent autophagy in C. elegans

A bacterial metabolite induces glutathione-tractable proteostatic damage, proteasomal disturbances, and PINK1-dependent autophagy in C. elegans

Por Martinez, B A, Kim, H, Ray, A, Caldwell, G A, Caldwell, K A
Publicado no Cell Death Dis (2015)

“...Gene-by-environment interactions are thought to underlie the majority of idiopathic cases...”
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16

Antioxidant enzymes in blood of patients with Friedreich's ataxia

Antioxidant enzymes in blood of patients with Friedreich's ataxia

Por Tozzi, G, Nuccetelli, M, Lo, B, Bernardini, S, Bellincampi, L, Ballerini, S, Gaeta, L, Casali, C, Pastore, A, Federici, G, Bertini, E, Piemonte, F
Publicado em 2002

“... may underlie the pathophysiology of Friedreich's ataxia, the most common inherited ataxia, due to GAA...”
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17

YBR/EiJ mice: a new model of glaucoma caused by genes on chromosomes 4 and 17

YBR/EiJ mice: a new model of glaucoma caused by genes on chromosomes 4 and 17

Por Nair, K. Saidas, Cosma, Mihai, Raghupathy, Narayanan, Sellarole, Michael A., Tolman, Nicholas G., de Vries, Wilhelmine, Smith, Richard S., John, Simon W. M.
Publicado no Dis Model Mech (2016)

“... glaucoma-susceptible strain and C57BL/6J as a glaucoma-resistant strain were performed to identify genetic...”
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18

Clinical spectrum of females with HCCS mutation: from no clinical signs to a neonatal lethal form of the microphthalmia with linear skin defects (MLS) syndrome

Clinical spectrum of females with HCCS mutation: from no clinical signs to a neonatal lethal form of the microphthalmia with linear skin defects (MLS) syndrome

Por van Rahden, Vanessa A, Rau, Isabella, Fuchs, Sigrid, Kosyna, Friederike K, de Almeida, Hiram Larangeira, Fryssira, Helen, Isidor, Bertrand, Jauch, Anna, Joubert, Madeleine, Lachmeijer, Augusta M A, Zweier, Christiane, Moog, Ute, Kutsche, Kerstin
Publicado em 2014

“... submicroscopic copy number losses, one of ~850 kb and one of ≥3 Mb, all covering HCCS, 1 nonsense, and one mosaic...”
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19

Excessive activity of cathepsin K is associated with cartilage defects in a zebrafish model of mucolipidosis II

Excessive activity of cathepsin K is associated with cartilage defects in a zebrafish model of mucolipidosis II

Por Petrey, Aaron C., Flanagan-Steet, Heather, Johnson, Steven, Fan, Xiang, De la Rosa, Mitche, Haskins, Mark E., Nairn, Alison V., Moremen, Kelley W., Steet, Richard
Publicado em 2012

“...The severe pediatric disorder mucolipidosis II (ML-II; also known as I-cell disease) is caused...”
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20

Oxidative stress contributes to outcome severity in a Drosophila melanogaster model of classic galactosemia

Oxidative stress contributes to outcome severity in a Drosophila melanogaster model of classic galactosemia

Por Jumbo-Lucioni, Patricia P., Hopson, Marquise L., Hang, Darwin, Liang, Yongliang, Jones, Dean P., Fridovich-Keil, Judith L.
Publicado em 2013

“... to galactose and found that both genes were induced, one by more than 40-fold. Combined, these results...”
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