Herbal extracts differentially inhibit oxidative effects caused by the biotransformation of nifurtimox, nitrofurantoin and acetaminophen on rat liver microsomes

Inflammation is a cellular defensive mechanism associated to oxidative stress. The administration of nitrofurantoin, nifurtimox and acetaminophen generates oxidative stress by their biotransformation through CYP450 system. The main adverse effect descri bed for the first two drugs...

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Detalhes bibliográficos
Publicado no:Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas
Main Authors: María E. Letelier, Pablo A. Iturra - Montecinos, Carlos A. Gallardo - Garrido
Formato: Artigo
Idioma:Inglês
Publicado em: Universidad de Santiago de Chile 2017
Assuntos:
Agrociencias
GST
Polyphenols
Antioxidants
Herbal thiols
Herbal extracts
Acesso em linha:https://www.redalyc.org/articulo.oa?id=85649864001
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