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Identification of three new mutations in the RB1 gene in patients with sporadic retinoblastoma in Colombia

Introduction. Retinoblastoma is a childhood cancer of the retina originated by altered or null retinoblastoma protein (pRb) expression. Genetic alterations in both RB1 alleles in the retinal cells are required for the development of retinoblastoma. In the sporadic form, non-hereditary RB1 gene mutat...

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書目詳細資料
發表在:Biomédica
Main Authors: Martha Lucía Serrano, Juan José Yunis
格式: Artigo
語言:Inglês
出版: Instituto Nacional de Salud 2013
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在線閱讀:https://www.redalyc.org/articulo.oa?id=84326221007
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