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Identification of three new mutations in the RB1 gene in patients with sporadic retinoblastoma in Colombia
Introduction. Retinoblastoma is a childhood cancer of the retina originated by altered or null retinoblastoma protein (pRb) expression. Genetic alterations in both RB1 alleles in the retinal cells are required for the development of retinoblastoma. In the sporadic form, non-hereditary RB1 gene mutat...
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| 發表在: | Biomédica |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Instituto Nacional de Salud
2013
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| 主題: | |
| 在線閱讀: | https://www.redalyc.org/articulo.oa?id=84326221007 |
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